16x130 - Matthew Fox, Carol Leifer, the All-American Rejects, a Top Ten List presented by Matthew Stafford

April 27, 2009

16x131 - Dolly Parton, Zachary Quinto

April 28, 2009

16x132 - Jennifer Garner, Tesla Motors CEO Elon Musk, Manchester Orchestra

April 29, 2009

16x133 - Regis Philbin, a performance by the Broadway cast of "Hair"

April 30, 2009

16x134 - Kiefer Sutherland, Jim Norton, Bat for Lashes

May 1, 2009

16x135 - Gordon Ramsay, Chris Pine, Keri Hilson with Kanye West

May 4, 2009

16x136 - Liev Schreiber, Dr. Sanjay Gupta, Franz Ferdinand

May 5, 2009

16x137 - Bruce Willis, Ben Harper & Relentless7

May 6, 2009

16x138 - Norm MacDonald, a Top Ten List presented by Leonard Nimoy, Animal Collective

May 7, 2009

16x139 - Matthew Broderick, Brian Regan, Chris Cornell

May 8, 2009

16x140 - Tom Hanks, the Killers

May 11, 2009

16x141 - Alec Baldwin, Maya Rudolph, Chrisette Michele

May 12, 2009

16x142 - Robin Williams, Wynton Marsalis

May 13, 2009

16x143 - Kid Scientists, Teri Hatcher, Rick Ross with Magazeen, a Top Ten List presented by Ron Howard

May 14, 2009

16x144 - John Goodman, Tommy Tiernan, Mastodon

May 15, 2009

16x145 - Ben Stiller, White Rabbits

May 18, 2009

16x146 - Jane Fonda, Piedmont Bird Callers, Kenny Chesney

May 19, 2009

16x147 - Stephen Colbert, General Motors Vice Chairman Bob Lutz, Grizzly Bear

May 20, 2009

16x148 - Amy Sedaris, Ed Helms, Jean Redpath

May 21, 2009

16x149 - Ricky Gervais, Green Day

May 22, 2009

16x150 - Bill Cosby, Helio Castroneves, Melody Gardot

June 1, 2009

16x151 - Jack Hanna, John Krasinski

June 2, 2009

16x152 - Jessica Biel, Zach Galifianakis, Steve Earle

June 3, 2009

16x153 - Elvis Costello, a Top Ten List presented by Neil Patrick Harris

June 4, 2009

16x154 - Paris Hilton, Calvin Borel, Steven Wright

June 5, 2009

16x155 - Howard Stern, Mos Def

June 8, 2009

16x156 - Julia Roberts, Black Eyed Peas

June 9, 2009

16x157 - Kathy Griffin, Stupid Human Tricks, Sonic Youth, an NBA Finals report by Phoenix Suns' Steve Nash

June 10, 2009

16x158 - Denzel Washington, the Jonas Brothers, a Top Ten List with Regis Philbin

June 11, 2009

16x159 - Sandra Bullock, Pete Correale, P.J. Harvey & John Parish

June 12, 2009

16x160 - Jack Black, M.A. Sanjayan

June 15, 2009

16x161 - Michelle Pfeiffer, Judah Friedlander, Ian McLagan & the Bump Band

June 16, 2009

16x162 - Ryan Reynolds, Padma Lakshmi, the Eels

June 17, 2009

16x163 - Danny DeVito, Bear Grylls, Phoenix

June 18, 2009

Dave welcomes the star of the FX network comedy, "It's Always Sunny in Philadelphia", Danny Devito. Topics include Danny's now infamous Youtube moment when it appeared he was drunk on the set. He claims he wasn't. Later, star of the Discovery Channel/Science Channel series, "Man vs. Wild", Bear Grylis stops by to discuss his series upcoming episode with superstar Will Farrell. Phoenix is the Musical Guest.

16x164 - Jada Pinkett Smith, Michael Cera, the Sounds

June 19, 2009

Jada Pinkett-Smith discusses her new role as a doctor in the TnT Tuesday night drama, "Hawthorne" and her oldest son, Jaden's new role in the Karate Kid remake, "Kung Fu Kid". Jada noting that the the family will be living in Hong Kong during the film's production. Michael Cerra discusses his role in the new film, "Year One", also starring Jack Black. Swedish Rock band, The Sounds, are the musical guests.

16x165 - Samuel L. Jackson, Emeril Lagasse, Iggy Pop & the Brighton Port Authority

June 22, 2009

16x166 - Sandra Day O'Connor, MSTRKRFT with John Legend, a Top Ten List presented by Lucas Glover

June 23, 2009

16x167 - Ray Romano, St. Vincent

June 24, 2009

16x168 - Johnny Depp, Megan Fox

June 25, 2009

16x169 - Martin Short, Regina Spektor

June 26, 2009

16x170 - Serena Williams, Hayden Panettiere, Conor Oberst and the Mystic Valley Band

July 6, 2009

16x171 - Sacha Baron Cohen, Joel McHale

July 7, 2009

16x172 - Queen Latifah, Emma Watson

July 8, 2009

16x173 - Daniel Radcliffe, Veronika Part, Levon Helm, a Top Ten List presented by Bruno

July 9, 2009

16x174 - Rainn Wilson, Larry Miller, Maxwell

July 10, 2009

16x175 - Jonah Hill, Gar Ryness, Kelly Clarkson

July 13, 2009

16x176 - Edie Falco, Michael Showalter, Wilco with Feist

July 14, 2009

16x177 - Paul McCartney, a Top Ten List presented by Bruce Willis

July 15, 2009

16x178 - Anderson Cooper, Anna Paquin, Grizzly Bear

July 16, 2009

16x179 - Tom Arnold, Metric, a Top Ten List presented by Dave's mom Dorothy

July 17, 2009

16x181 - Kevin Spacey, Jesse James, the Flatlanders, a Top Ten List presented by Stewart Cink

July 21, 2009

16x182 - Tracy Morgan, Leslie Mann, Diane Birch

July 22, 2009

16x183 - Sean "Diddy" Combs, Vera Farmiga, Ginuwine with Missy Elliott

July 23, 2009

16x184 - Amy Poehler, Nick Griffin, Judy Collins

July 24, 2009

16x185 - Eric Bana, Dave Matthews Band, a Top Ten List presented by Chicago White Sox star Mark Buehrle

July 27, 2009

16x186 - Katie Couric, Silversun Pickups

July 28, 2009

16x187 - Amy Adams, Tom Dreesen, Elbow

July 29, 2009

16x188 - Adam Sandler, Cage the Elephant

July 30, 2009

Quentin Tarantino, Eric Ripert, and Robert Cray are the scheduled guests.

16x189 - Regis Philbin, Ted Alexandro, Dave Matthews Band

July 31, 2009

16x190 - Quentin Tarantino, Eric Ripert, Robert Cray

August 17, 2009

16x191 - Donald Trump, Diane Kruger, Billy Currington, a Top Ten List presented by Britney Spears

August 18, 2009

16x192 - Mike Myers, Ken Burns

August 19, 2009

16x193 - Anna Wintour, Mark Teixeira

August 24, 2009

16x194 - Renee Zellweger, Gary Mule Deer

August 20, 2009

Mary-Louise Parker, Eugene Levy, and Jet are the scheduled guests.

16x195 - Christina Applegate, Brendan Benson, Patton Oswalt

August 21, 2009

16x196 - Anna Wintour, Mark Teixeira

August 24, 2009

16x197 - Mary-Louise Parker, Eugene Levy, Jet

August 25, 2009

16x198 - Anne Heche, Jim Parsons, Care Bears on Fire

August 26, 2009

16x199 - Andy Roddick, Rachael Ray, Mutemath

August 27, 2009

16x200 - Artie Lange, Todd Barry, Imogen Heap

August 28, 2009