6x25 - Dr. Sanjay Gupta, Sarah Cooper

October 27, 2020

Stephen welcomes medial reporter Dr. Sanjay Gupta and author Sarah Cooper.

6x26 - Jaime Harrison, Elvis Costello

October 28, 2020

Stephen welcomes politician Jaime Harrison, plus an interview with and a musical performance by Elvis Costello.

6x27 - Julie Andrews, Amy Walter, Sam Smith

October 29, 2020

Stephen welcomes actress Julia Andrews, political analyst Amy Walter with a musical performance by Sam Smith.

6x28 - Jon Stewart, Neil deGrasse Tyson

October 30, 2020

Stephen welcomes actor Jon Stewart and astrophysicist Neil deGrasse Tyson.

6x29 - John Oliver, Cher, Jojo

November 2, 2020

Stephen welcomes TV Host John Oliver, singer Cher, plus a musical performance by Jojo.

6x30 - Shepard Smith, Leon Bridges, Lucky Daye

November 4, 2020

Stephen welcomes CNBC's Chief general anchor Shepard Smith, and a musical performance by Leon Bridges and Lucky Daye.

6x31 - Larry Wilmore, Laura Benanti

November 5, 2020

Stephen welcomes comedian Larry Wilmore and a musical performance by Laura Benanti.

6x32 - Alex Wagner, John Heilemann, Mark McKinnon, Charlamagne Tha God, Jena Friedman, Maz Jobrani, Arcade Fire

November 6, 2020

Network presentation of The Late Show's Showtime Election Night Special, The hosts of "The Circus": Alex Wagner, John Heilemann and Mark McKinnon, Charlamagne Tha God, Jena Friedman, Maz Jobrani, and a musical performance by Arcade Fire.

6x33 - Stacey Abrams, Thomas Middleditch

November 9, 2020

Stephen welcomes politician Stacey Abrams and actor Thomas Middleditch.

6x34 - Hugh Grant, Sturgill Simpson

November 10, 2020

Stephen welcomes actor Hugh Grant and singer Sturgill Simpson.

6x35 - Olivia Colman, Gillian Anderson, Kylie Minogue

November 11, 2020

Stephen welcomes actress Olivia Colman, actress Gillian Anderson, singer Kylie Minogue.

6x36 - Michael Moore, Sara Bareilles, Steve Carell

November 12, 2020

Stephen welcomes filmmaker Michael Moore, singer Sara Bareilles and a special appearance by actor Steve Carell.

6x37 - Jake Tapper, BENEE

November 16, 2020

Stephen welcomes American Journalist Jake Tapper, and a musical performance by BENEE.

6x38 - Lewis Hamilton, Andrea Bocelli

November 17, 2020

Stephen welcomes Formula 1 racing driver Lewis Hamilton, and a musical performance by Andrea Bocelli.

6x39 - 11/18/20 (Matthew McConaughey, Cedric the Entertainer)

November 18, 2020

Stephen welcomes actor Matthew McConaughey and actor Cedric the Entertainer.

6x40 - 11/19/20 (LL Cool J, Dave Grohl, Foo Fighters)

November 19, 2020

Stephen welcomes actor LL Cool J, from the CBS drama NCIS: Los Angeles, musician Dave Grohl and a musical performance by Foo Fighters.

6x41 - Glenn Close, Kane Brown, Swae Lee, Khalid

November 23, 2020

Glenn Close, Kane Brown, Swae Lee, Khalid

6x42 - President Barack Obama, Brittany Howard

November 24, 2020

6x43 - Rob Corddry, John Lithgow, Chef José Andrés

November 25, 2020

Rob Corddry, John Lithgow, Chef José Andrés

6x44 - President Barack Obama, Vol. 2

November 30, 2020

President Barack Obama, Vol. 2

6x45 - Bryan Cranston, Cori Bush

December 1, 2020

Bryan Cranston, Cori Bush

6x46 - Kate Winslet, Michael Eric Dyson

December 2, 2020

Kate Winslet, Michael Eric Dyson

6x47 - Christopher Krebs, Aubrey Plaza

December 3, 2020

Christopher Krebs, Aubrey Plaza

6x48 - Common, Andrea Bocelli

December 4, 2020

Common, Andrea Bocelli

6x49 - Meryl Streep, Chris Stapleton

December 7, 2020

Meryl Streep, Chris Stapleton

6x50 - John Dickerson, Emily Bazelon, David Plotz, Greta Van Fleet

December 8, 2020

John Dickerson, Emily Bazelon, David Plotz, Greta Van Fleet

6x51 - Rachel Maddow, Megan Thee Stallion

December 9, 2020

Rachel Maddow, Megan Thee Stallion

6x52 - James Corden, Fleet Foxes

December 10, 2020

James Corden, Fleet Foxes

6x53 - New Zealand Special

December 11, 2020

New Zealand Special

6x54 - Chance The Rapper, Christopher Walken, Laura Benanti

December 14, 2020

Chance The Rapper, Christopher Walken, Laura Benanti

6x55 - Whoopi Goldberg, Anderson Cooper, Andy Cohen

December 15, 2020

Whoopi Goldberg, Anderson Cooper, Andy Cohen

6x56 - Tom Hanks, Leslie Odom Jr.

December 16, 2020

Tom Hanks, Leslie Odom Jr.

6x57 - Joseph R. Biden, Dr. Jill Biden, Jon Batiste

December 17, 2020

Joseph R. Biden, Dr. Jill Biden, Jon Batiste

6x58 - George Clooney

December 18, 2020

George Clooney

6x59 - Stacey Abrams, RuPaul Charles, Maren Morris

January 4, 2021

Stacey Abrams, RuPaul Charles, Maren Morris

6x60 - Dr. Sanjay Gupta, Anya Taylor-Joy

January 5, 2021

Dr. Sanjay Gupta, Anya Taylor-Joy

6x61 - Amy Klobuchar, Adam Kinzinger, Jamila Woods

January 6, 2021

Amy Klobuchar, Adam Kinzinger, Jamila Woods

6x62 - Rachel Brosnahan, Julien Baker

January 7, 2021

Rachel Brosnahan, Julien Baker

6x63 - George Clooney, Tom Hanks, Meryl Streep, The Mountain Goats

January 8, 2021

George Clooney, Tom Hanks, Meryl Streep, The Mountain Goats

6x64 - Chris Rock, Aubrey Plaza, Joss Stone

January 11, 2021

Chris Rock, Aubrey Plaza, Joss Stone

6x65 - James Comey, Lili Reinhart

January 12, 2021

James Comey, Lili Reinhart

6x66 - Samantha Bee, Paul Mescal

January 13, 2021

Samantha Bee, Paul Mescal

6x67 - Bernie Sanders, FINNEAS

January 14, 2021

Bernie Sanders, FINNEAS

6x68 - John Heilemann, Mark McKinnon & Alex Wagner, The War On Drugs

January 15, 2021

John Heilemann, Mark McKinnon & Alex Wagner, The War On Drugs

6x69 - Cory Booker, Laura Benanti, Infinity Song

January 18, 2021

Cory Booker, Laura Benanti, Infinity Song

6x70 - Jason Segel, Black Pumas

January 19, 2021

Jason Segel, Black Pumas

6x71 - Jon Lovett, Jon Favreau, Tommy Vietor, Peter CottonTale, Chance the Rapper, Cynthia Erivo, Chicago Children's Choir, Kofi Lost

January 20, 2021

Jon Lovett, Jon Favreau, Tommy Vietor, Peter CottonTale, Chance the Rapper, Cynthia Erivo, Chicago Children's Choir, Kofi Lost

6x72 - Priyanka Chopra Jonas, Derek DelGaudio, Frank Oz

January 21, 2021

Priyanka Chopra Jonas, Derek DelGaudio, Frank Oz

6x73 - Serena Williams, Dayglow

January 25, 2021

Stephen welcomes professional tennis player Serena Williams and a musical performance by Dayglow.

6x74 - Colin Firth, Stanley Tucci, Adrianne Lenker

January 26, 2021

Stephen welcomes actor Colin Firth, actor Stanley Tucci, and a musical performance by Adrianne Lenker.

6x76 - Viggo Mortensen, Charles Blow

January 28, 2021

Stephen welcomes actor Viggo Mortensen and journalist Charles Blow.

6x77 - Joe Biden, Jill Biden, Kamala Harris

January 29, 2021

Stephen welcomes President Joe Biden, First Lady Jill Biden, and Vice President Kamala Harris.

6x78 - Ethan Hawke, Mickey Guyton

February 1, 2021

Stephen welcomes actor Ethan Hawke and a musical performance by Mickey Guyton.

6x79 - Zendaya, James Martin

February 2, 2021

Stephen welcomes actress Zendaya and Father James Martin.

6x80 - Salma Hayek, Mark Harris

February 3, 2021

Stephen welcomes actress Salma Hayek and journalist Mark Harris.

6x81 - Tiffany Haddish, H.E.R.

February 4, 2021

Stephen welcomes actress Tiffany Haddish and a musical performance by H.E.R.

6x82 - Robert Downey Jr., Tiffany Haddish, Metallica

February 7, 2021

Stephen welcomes actor Robert Downey Jr., actress Tiffany Haddish, and a musical performance by Metallica.

6x83 - Queen Latifah, Steven Yeun

February 8, 2021

Stephen welcomes actress Queen Latifah and actor Steven Yeun.

6x84 - John Oliver, Ingrid Andress

February 9, 2021

Stephen welcomes TV host John Oliver and a musical performance by Ingrid Andress.

6x85 - Kristen Wiig, Rebecca Breeds

February 10, 2021

Stephen welcomes actress Kristen Wiig and actress Rebecca Breeds.

6x86 - Blake Shelton

February 11, 2021

Stephen welcomes a talk and musical performance by Blake Shelton.

6x87 - Bill Gates, Tune-Yards

February 22, 2021

Stephen welcomes co-founder of Microsoft Bill Gates and a musical performance by Tune-Yards.

6x88 - Billie Eilish, Anna Palmer, Jake Sherman

February 23, 2021

Stephen welcomes singer Billie Eilish, Punchbowl News Co-Founders Anna Palmer & Jake Sherman.

6x89 - Arsenio Hall, Tim Meadows, Celeste

February 24, 2021

Stephen welcomes actor Arsenio Hall, actor Tim Meadows and a musical performance by Celeste.

6x90 - Regina King, Jamaal Bowman, Vic Mensa, Wyclef Jean, Peter Cottontale

February 25, 2021

Stephen welcomes actress Regina King, a special appearance by Rep. Jamaal Bowman, and a musical performance by Vic Mensa featuring Wyclef Jean and Peter Cottontale.

6x91 - Andy Samberg, Clarissa Ward

March 1, 2021

Stephen welcomes actor Andy Samberg and journalist Clarissa Ward.

6x92 - Neil deGrasse Tyson, Jon Batiste

March 2, 2021

Stephen welcomes astrophysicist Neil deGrasse Tyson and a musical performance by Jon Batiste.

6x93 - Paul Bettany, Metallica

March 3, 2021

Stephen welcomes actor Paul Bettany and a musical performance by Metallica.

6x94 - Jane Fonda, The Hosts of “Virtue Signal”, Kings of Leon

March 4, 2021

Stephen welcomes actress Jane Fonda, the Hosts of “Virtue Signal”, and a musical performance by Kings of Leon.

6x95 - Nicolle Wallace, Michaela Coel, Kings of Leon

March 8, 2021

Stephen welcomes TV host Nicolle Wallace, actress Michaela Coel, and a musical performance by Kings of Leon.

6x96 - Riz Ahmed, Janelle Monáe

March 9, 2021

Stephen welcomes actor Riz Ahmed and a musical performance by Janelle Monáe.

6x97 - Emmanuel Acho, Gina Yashere

March 10, 2021

Stephen welcomes sports analyst Emmanuel Acho and comedian Gina Yashere.

6x98 - Aaron Paul, Billy Crystal, Lake Street Dive

March 11, 2021

Stephen welcomes actor Aaron Paul, actor Billy Crystal, and a musical performance by Lake Street Dive.

6x99 - Dr. Anthony Fauci

March 12, 2021

Stephen welcomes Dr. Anthony Fauci.

6x100 - Ringo Starr, Laura Benanti

March 15, 2021

Stephen welcomes musician Ringo Starr and a special appearance by actress Laura Benanti.

6x101 - Lupita Nyong'o, Martin Freeman

March 16, 2021

Stephen welcomes actress Lupita Nyong’o and actor Martin Freeman.

6x102 - Earvin “Magic” Johnson, Eric Andre

March 17, 2021

Stephen welcomes businessman Earvin “Magic” Johnson and comedian Eric Andre.

6x103 - Chuck Schumer, Jared Leto, LANCO

March 18, 2021

Stephen welcomes Senator Chuck Schumer, actor Jared Leto and a musical performance by LANCO.

6x104 - Robert Downey Jr., Walter Isaacson, Sebastian Yatra, Guaynaa

March 22, 2021

Stephen welcomes actor Robert Downey Jr., author Walter Isaacson, and a musical performance by Sebastian Yatra and Guaynaa.

6x105 - Dana Carvey, Imagine Dragons

March 23, 2021

Stephen welcomes actor Dana Carvey and a musical performance by Imagine Dragons.

6x106 - Sharon Stone, Ken Burns

March 24, 2021

Stephen welcomes actress Sharon Stone and filmmaker Ken Burns.

6x107 - John Cena, Tammy Duckworth

April 5, 2021

Stephen welcomes TV host John Cena and Senator Tammy Duckworth.

6x108 - Ronan Farrow, Brandi Carlile

April 6, 2021

Stephen welcomes journalist Ronan Farrow and singer Brandi Carlile.

6x109 - Leslie Odom Jr., Michio Kaku

April 7, 2021

Stephen welcomes actor Leslie Odom Jr. and physicist Michio Kaku.

6x110 - Hank Azaria, Cheap Trick

April 8, 2021

Stephen welcomes actor Hank Azaria and a musical performance by Cheap Trick.

6x111 - John Boehner, Shelley

April 12, 2021

6x112 - Daniel Kaluuya, Lucy Dacus, Taylor Swift

April 13, 2021

6x113 - Willie Geist, Maria Bakalova

April 14, 2021

6x114 - Amanda Seyfried, Ashley McBryde

April 16, 2021

6x115 - Anthony Hopkins, Florian Zeller, Mazie Hirono

April 19, 2021

6x116 - Cher, Bradley Whitford

April 20, 2021

Stephen welcomes singer Cher, and a musical performance by Sam Williams.

6x117 - Ed Helms, Susan Page

April 21, 2021

Stephen welcomes actor Ed Helms and journalist Susan Page.

6x118 - Joe Scarborough, Mika Brzezinski, Bebe Rexha

April 22, 2021

Stephen welcomes TV host Joe Scarborough, journalist Mika Brzezinski, and a musical performance by Bebe Rexha.

6x119 - Anthony Mackie, Terry Gross

April 26, 2021

Stephen welcomes actor Anthony Mackie and radio show host Terry Gross.

6x120 - Sen. Amy Klobuchar, Kyle MacLachlan

April 27, 2021

Stephen welcomes Senator Amy Klobuchar and actor Kyle MacLachlan.

6x121 - Sen. Bernie Sanders, Julia Michaels

April 28, 2021

Stephen welcomes Senator Bernie Sanders and a musical performance by Julia Michaels.

6x122 - Mila Kunis, Sara Kays

April 29, 2021

Stephen welcomes actress Mila Kunis and a musical performance by Sara Kays.

6x123 - Jane Fonda, John Oliver, Ringo Starr, Teddy Swims

April 30, 2021

Stephen welcomes actress Jane Fonda, TV personality John Oliver, musician Ringo Starr, and a musical performance by Teddy Swims.

6x124 - Jake Tapper, Billie Eilish

May 10, 2021

Stephen welcomes journalist Jake Tapper and musician Billie Eilish.

6x125 - Michelle Obama

May 11, 2021

Stephen welcomes former first lady Michelle Obama.