22x1 - Kidnapped - Shawn Hornbeck's Incredible Story

September 24, 2008

22x2 - Into Thin Air

October 18, 2008

The 1976 disappearance of Jean Zapata, a wife and mother in Madison, Wis., is investigated.

22x3 - Did the Doctor Kill the Doctor?

October 25, 2008

22x4 - Blood and Money on Horseshoe Bay

November 1, 2008

22x5 - Vegas Heat

November 8, 2008

22x6 - Truth on Trial

November 15, 2008

22x7 - Sign of the Times

November 22, 2008

22x8 - Drawn to Murder

November 29, 2009

22x9 - The Guessing Game

December 6, 2008

22x11 - Power, Passion and Poison - Revisited

December 20, 2008

22x12 - Who Killed Toni Heartstring

January 10, 2009

22x13 - Peace, Love and Murder

January 17, 2008

22x14 - Lady In The Harbor

January 24, 2009

22x15 - Conspiracy To Kill

January 31, 2009

22x16 - An Invisible Enemy

February 7, 2009

22x17 - Picture Perfect

March 7, 2009

22x18 - Toxic

March 14, 2009

The 2000 poisoning death of Eric Miller, a pediatric AIDS researcher in Raleigh, is investigated.

22x19 - The Curious Case Of Colonel Shue

March 28, 2009

22x20 - American Girl, Italian Nightmare

April 11, 2009

22x21 - Craigslist: Classified For Murder

April 25, 2009

22x22 - Dark Voyage

May 2, 2009

22x23 - Catch Her If You Can

May 9, 2009

22x24 - Daddy's Girl

May 16, 2009

22x25 - Deep Secret

June 2, 2009

22x26 - Did The Doctor Kill The Doctor? - Revisited

June 13, 2009