5x42 - Vera Wang

March 22, 2011

Designer Vera Wang on her new fragrance, Preppy Princess; Round table discussion with comics Chris Hardwick, Jo Koy, and Sarah Colonna.

5x43 - Carla Gugino

March 23, 2011

Actress Carla Gugino on her new film, Elektra Luxx; Round table discussion with comics Chris Franjola, Loni Love, and Greg Proops.

5x44 - Brittany Snow

March 24, 2011

Brittany Snow from Harry's Law and the cover of Maxim joins us tonight. Comedian Jim Norton, comedian Jen Kirkman and TV personality Ross Mathews

5x45 - Mireya Mayor

March 28, 2011

Author of Pink Boots and a Machete, National Geographic's Mireya Mayor is here with some animal friends. Comedian Ben Gleib, comedian Fortune Feimster and comedian Josh Wolf.

5x46 - Blake Shelton

March 29, 2011

Tonight we gladly welcome back country superstar Blake Shelton. E!'s own Michael Yo, comedian Heather McDonald and comedian Jo Koy

5x47 - Jerry Weintraub

March 30, 2011

Legendary film producer and Jew Jerry Weintraub is here with his documentary, His Way. Comedian Joe Matarese, actress-comedian Arden Myrin and comedian John Caparulo

5x48 - Shenae Grimes

March 31, 2011

From Scream 4 Shenae Grimes is on the show tonight. Comedian Dov Davidoff, comedian Dan Levy and TV personality Ross Mathews

5x49 - James Marsden

April 4, 2011

From the No. 1 film Hop, James Marsden joins us tonight. Comedian Brad Wollack, writer Diablo Cody and comedian Gary Valentine

5x50 - Mark Macdonald

April 5, 2011

Nutritionist and author or Body Confidence Mark Macdonald is here. Comedian Chris Hardwick, comedian Sarah Colonna and comedian Matt Braunger

5x51 - Zooey Deschanel

April 6, 2011

Zooey Deschanel is here telling us about her new movie, Your Highness. Comedian Josh Wolf, comedian Erin Gibson and comedian Jo Koy

5x52 - Elizabeth Berkley

April 7, 2011

Actress Elizabeth Berkley is here with her new book Ask Elizabeth. Comedian Chris Franjola, comedian Jeff Wild and TV personality Ross Mathews

5x53 - Joshua Jackson

April 11, 2011

Anything can happen with Fringe's Joshua Jackson on the show tonight. Comedian Bobby Lee, comedian Heather McDonald and comedian Ryan Stout

5x54 - Adam Brody

April 12, 2011

Find out if Adam Brody lives of dies in Scream 4 tonight. Comedian Bill Bellamy, actress-comedian Arden Myrin and comedian Josh Wolf

5x55 - JoAnna Garcia Swisher

April 13, 2011

JoAnna Garcia Swisher from Better With You joins us tonight. Comedian John Caparulo, comedian Jen Kirkman and comedian Greg Fitzsimmons

5x56 - Hayden Panettiere

April 14, 2011

Want to go double or nothing (see Tuesday) on Hayden Panettiere living or dying in Scream 4? Comedian Fortune Feimster, comedian Natasha Leggero and comedian Sarah Colonna

5x57 - Robin Wright

April 18, 2011

From the new film The Conspirator Robin Wright is here. Comedian Josh Wolf, comedian Natasha Leggero and comedian Michael Yo

5x58 - Simon LeBon & John Taylor

April 19, 2011

From Duran Duran Simon LeBon and Nick Rhodes are here to talk their latest CD All You Need Is Now. Comedian Ben Gleib, comedian Brad Wollack and comedian Jo Koy

5x59 - Ziggy Marley

April 20, 2011

Ziggy Marley tells us about his new comic book Marijuanaman tonight. Comedian Lavell Crawford, comedian Heather McDonald, and TV personality Ross Mathews

5x60 - Malin Akerman

April 21, 2011

The very Swedish Malin Akerman is here tonight with her new movie The Bang Bang Club. Comedian Chris Franjola, comedian Loni Love and comedian Chris Hardwick

5x61 - Gwyneth Paltrow

April 25, 2011

Gwyneth Paltrow is on the show tonight with her new book My Father's Daughter. Comedian Dan Levy, comedian-actress Arden Myrin and comedian Bobby Lee

5x62 - Taylor Momsen

April 26, 2011

The Pretty Reckless' Taylor Momsen talks Gossip Girl and her album Light Me Up. Comedian John Caparulo, comedian Sarah Colonna and comedian Jo Koy

5x63 - Jason Priestley

April 27, 2011

Comedian Matt Braunger, comedian Jen Kirkman and comedian T.J. Miller

5x64 - Mary McCormack

April 28, 2011

From In Plain Sight, our good friend Mary McCormack is here. Comedian Fortune Feimster, comedian Gary Valentine and TV personality Ross Mathews

5x65 - Tyrese Gibson

May 2, 2011

Tyrese Gibson, from the No. 1 movie in America, Fast Five, is on the show tonight. Comedian Josh Wolf, comedian Heather McDonald and comedian Brad Wollack

5x66 - Paula Patton

May 3, 2011

From the new film Jumping the Broom the delightful Paula Patton is here. Comedian Chris Hardwick, comedian Loni Love and comedian Jo Koy

5x67 - Melissa McCarthy

May 4, 2011

Melissa McCarthy is here from the very funny new movie Bridesmaids. Comedian Joe Matarese, comedian Chris Franjola and TV personality Ross Mathews

5x68 - Dita Von Teese

May 5, 2011

Dita Von Teese is here to fill us in on her latest endeavors including her MargaDita. Comedian Fortune Feimster, comedian John Caparulo and comedian Greg Fitzsimmons

5x69 - Will Ferrell

May 9, 2011

From the new film Everything Must Go, Will Ferrell is here tonight. Comedian Jen Kirkman, comedian Whitney Cummings and comedian Jo Koy

5x70 - Paul Bettany

May 10, 2011

Paul Bettany shows us he's an action star in his new film Priest tonight. Comedian Jeff Wild, comedian Sarah Colonna and comedian Chris Franjola

5x71 - Judd Apatow

May 12, 2011

Judd Apatow is here to tell us about his new film Bridesmaids. Comedian Jim Norton, comedian Natasha Leggero and comedian Josh Wolf.

5x72 - Kelly Osbourne

May 16, 2011

One of the hosts of E!'s Fashion Police Kelly Osbourne is on the show tonight. Comedian Fortune Feimster, comedian John Caparulo and comedian Loni Love

5x73 - Kellan Lutz

May 17, 2011

Kellan Lutz is here with his new film Love, Wedding, Marriage. Comedian Greg Proops, comedian Heather McDonald and comedian Jo Koy

5x74 - Maya Rudolph

May 18, 2011

From the very funny film Bridesmaids. Maya Rudolph is here. Comedian Josh Wolf, comedian Mo Mandel and TV personality Ross Mathews

5x75 - Lucy Liu

May 19, 2011

We gladly welcome back Lucy Liu, star of Kung Fu Panda 2, to the show. Comedian Brad Wollack, actress-comedian Arden Myrin and E! News' Michael Yo

5x76 - Randy Jackson

May 23, 2011

Our favorite dawg, American Idol's Randy Jackson is here and In It to Win It. Comedian Chris Hardwick, comedian Sarah Colonna and comedian Bobby Lee

5x77 - Justin Bartha

May 24, 2011

From The Hangover Part II, Justin Bartha is on the show tonight. Comedian Ben Gleib, comedian Jo Koy and comedian Gary Valentine

5x78 - Matthew Morrison

May 25, 2011

Glee's Matthew Morrison is here and he has a new self-titled debut CD. Comedian Josh Wolf, comedian Dov Davidoff and Comedian Natasha Leggero.

5x79 - Eva Mendes

May 26, 2011

Eva Mendes tells us about her latest film, Last Night, on the show tonight. Comedian Chris Franjola, comedian Jen Kirkman, and TV personality Ross Mathews.

5x80 - Donald Schultz

May 30, 2011

Donald Schultz is back with some new animal friends. Comedian Whitney Cummings, comedian Chris Franjola and comedian Brad Wollack.

5x81 - John Caparulo, Jo Koy, Fortune Feimster

May 31, 2011

5x82 - Kareem Abdul-Jabbar

June 1, 2011

5x83 - Piper Perabo

June 2, 2011

From the show Covert Affairs fellow New Jersian Piper Perabo is here. Comedian Matt Braunger, comedian Heather McDonald and comedian Josh Wolf.

5x84 - Lauren Conrad

June 6, 2011

Lucky magazine cover girl Lauren Conrad is here telling us all about her new clothing line. Comedian Chris Franjola, comedian Sarah Colonna and comedian Ben Gleib.

5x85 - James Van Praagh

June 7, 2011

Author of Growing Up in Heaven, medium James Van Praagh is on the show tonight. Comedian Natasha Leggero, comedian Jo Koy and comedian Ryan Stout

5x86 - Single Staffer

June 8, 2011

Comedian-host Rove McManus, comedian Jen Kirkman and TV personality Ross Mathews

5x87 - Gene Simmons

June 9, 2011

From Gene Simmons Family Jewels Gene Simmons rocks out with us tonight. Comedian Bobby Lee, actress-comedian Arden Myrin and comedian Josh Wolf

5x88 - Jada Pinkett Smith

June 13, 2011

Star and executive producer of HawthoRNe Jada Pinkett Smith is here. Comedian Margaret Cho, comedian Fortune Feimster and TV personality Ross Mathews

5x89 - Fred Durst

June 14, 2011

Limp Bizkit has new album, Gold Cobra, and Fred Durst is here to tell us about it, and it's 2011. E! Correspondent Michael Yo, comedian Jo Koy and comedian Heather McDonald

5x90 - Padma Lakshmi

June 15, 2011

If you're a big Padma Lakshmi fan—and who isn't—tune in tonight to learn all about Bravo's Padmathon. Comedian-host Chris Hardwick, comedian John Caparulo and comedian Josh Wolf

5x91 - Connie Britton

June 16, 2011

Connie Britton (Mrs. Coach!) from Friday Night Lights is here: Clear eyes, full hearts can't lose. Comedian Mo Mandel, comedian Loni Love and comedian Brad Wollack

5x93 - Emily Mortimer

June 21, 2011

Emily Mortimer from the highly anticipated Cars 2 is on the show tonight. Comedian Josh Wolf, comedian Jo Koy and comedian Sarah Colonna.

5x94 - Kelly Slater

June 22, 2011

Ten-time world champion Pro Surfer Kelly Slater is here. Comedian Matt Braunger, actress-omedian Arden Myrin and TV personality Ross Mathews.

5x95 - Gabourey Sidibe

June 23, 2011

Gabourey Sidibe from The Big C makes her return to the show tonight. Comedian Greg Fitzsimmons, Comedian Jen Kirkman and comedian Whitney Cummings.

5x96 - Cooking w/ Roy and Chuy

June 27, 2011

5x97 - Liv Tyler

June 28, 2011

Tonight we welcome Liv Tyler from the movie The Ledge. Comedian Loni Love, comedian Jo Koy and comedian Gary Valentine

5x98 - Leslie Bibb

June 29, 2011

5x99 - Rosie Huntington-Whiteley

June 30, 2011

From Transformers: Dark of the Moon, Rosie Huntington-Whiteley is here. Comedian Fortune Feimster, comedian Josh Wolf and comedian Ben Gleib

5x100 - Jennifer Aniston

July 4, 2011

Actress Jennifer Aniston on her new movie Horrible Bosses; Round table discussion with comics Jo Koy, Arden Myrin, and Chris Franjola

5x101 - Rosario Dawson

July 5, 2011

Actress Rosario Dawson on her new movie Fire with Fire; Round table discussion with comics Joe Matarese, Ross Mathews, and Sarah Colonna

5x102 - Jason Sudeikis

July 7, 2011

From Horrible Bosses Jason Sudeikis is here. Comedian Jen Kirkman, comedian Josh Wolf and comedian Bobby Lee

5x103 - Grace Potter

July 18, 2011

Comedian John Caparulo, comedian Josh Wolf and comedian Loni Love

5x104 - Roseanne Barr

July 19, 2011

5x105 - Giuliana and Bill Rancic

July 20, 2011

5x106 - Rose Byrne

July 21, 2011

5x107 - Joe Manganiello

July 25, 2011

Round table comics include Michael Yo (@MichaelYo), Jen Kirkman (@JenKirkman) and Ross Mathews (@helloross). Tonight's guest is Joe Manganiello who plays the character Alcide on "True Blood".

5x108 - Jo Koy, Natasha Leggero and Jeff Wild

July 26, 2011

Round table comics include Jeff Wild (@jiffywild), Natasha Leggero (@natashaleggero) and Jo Koy (@JoKoy).

5x109 - Vanessa Carlton

July 27, 2011

Round table comics include Chris Franjola (@ChrisFranjola), Arden Myrin (@ArdinMyrin) and Bobby Lee (@bobbyleelive). Tonight's guest, Vanessa Carlton (@VanessaCarlton), just released her new CD "Rabbits OnThe Run".

5x110 - Taryn Manning

July 28, 2011

Round table comics include Josh Wolf (@joshwolfcomedy), Gary Valentine (@Cmplmnt_Accptd) and Matt Braunger (@Braunger). Taryn Manning (@TarynManning) is on the show tonight to tell us about her latest film, "The Perfect Age of Rock 'n' Roll".

5x111 - Sharon Osbourne

August 1, 2011

Round table comics include John Caparulo (@JohnCaparulo), Fortune Feimster (@fortunefunny) and Ben Gleib (@bengleib). We welcome back "America's Got Talent" judge Sharon Osbourne to the show tonight.

5x112 - Martha Plimpton

August 2, 2011

Martha Plimpton on her show Raising Hope; Round table discussion with comics Joe Matarese, Sarah Colonna, and Ross Mathews.

5x113 - Lisa Kudrow

August 3, 2011

Actress Lisa Kudrow on her new show Web Therapy; Round table discussion with comics Jo Koy, Heather McDonald, and Brad Wollack.

5x114 - Mary McCormack

August 4, 2011

Actress Mary McCormack on her show In Plain Sight; Round table discussion with comics Josh Wolf, Loni Love, and Ryan Stout.

5x115 - Michael Vartan

August 8, 2011

Actor Michael Vartan from "Colombiana". Round table comics include Mo Mandel (@momandel), Arden Myrin (@ArdenMyrin) and Ross Mathews (@HelloRoss).

5x116 - Rose McGowan

August 9, 2011

Actress Rose McGowan on her movie Conan The Barbarian 3D; Round table discussion with comics Jo Koy, Heather McDonald, and Bobby Lee.

5x117 - Bryce Dallas Howard

August 10, 2011

Actress Bryce Dallas Howard on her movie The Help; Round table discussion with comics Chris Hardwick, Jen Kirkman, and Matt Braunger.

5x118 - Trace Adkins

August 11, 2011

Country singer Trace Adkins on hosting American Country Awards; Round table discussion with comics Josh Wolf, Chris Franjola, and Fortune Feimster.

5x119 - Elizabeth Banks

August 15, 2011

Actress Elizabeth Banks on her new movie The Hunger Games; Round table discussion with comics Josh Wolf, Sarah Colonna, and Greg Fitzsimmons.

5x120 - Denis Leary

August 16, 2011

Actor Denis Leary on the final season of Rescue Me; Round table discussion with comics Jo Koy, Loni Love, and Jeff Wild.

5x121 - Anne Hathaway

August 17, 2011

Actress Anne Hathaway on her movie The Dark Knight Rises; Round table discussion with comics Greg Proops, Heather McDonald, and Ross Mathews.

5x122 - Christopher Mintz-Plasse

August 18, 2011

Actor Christopher Mintz-Plasse on his movie Fright Night 3D; Round table discussion with comics Brad Wollack, Fortune Feimster, and Dov Davidoff.

5x123 - Joey Lawrence

August 22, 2011

Round table guest host Ross Mathews with comics Chris Franjola (@ChrisFranjola), Arden Myrin (@ArdenMyrin) and Josh Wolf (@JoshWolfComedy). Tonight's guest is Joey Lawrence (@joeylawrence).

5x124 - Zoe Saldana

August 23, 2011

Round table comics include Ben Gleib (@BenGleib), Heather McDonald (@HeatherMcDonald) and Gary Valentine (@Gary_Valentine). Tonight's guest is Zoe Saldana (@zoesaldana).

5x125 - Rashida Jones

August 24, 2011

Round table comics include Dov Davidoff (@Dovdavidoff), Sarah Colonna (@SarahColonna) and Matt Braunger (@Braunger). Tonight's guest, Rashida Jones, plays a big lesbian lawyer in "Our Idiot Brother".

5x126 - Jessica Chastain

August 25, 2011

Round table comics include Chris Hardwick (@nerdist),Jen Kirkman (@JenKirkman) and Ryan Stout (@StoutRyan). Jessica Chastain plays Celia Foote in "The Help".

5x127 - Paul Rudd

August 29, 2011

5x128 - Snooki

August 30, 2011

Round table comics include Bill Bellamy (@BILLBELLAMY), Fortune Feimster (@fortunefunny) and Jo Koy (@Jokoy). "Jersey Shore's" Snooki is on the show tonight.

5x129 - Ashley Rickards

August 31, 2011

Round table comics include John Caparulo (@JohnCaparulo), Josh Wolf (@joshwolfcomedy) and Jeff Wild (@jiffywild). From MTV's "Awkward," Ashley Rickards (@AshRickards) is here.

5x130 - Lake Bell

September 1, 2011

Round table comics include Brad Wollack (@BradWollack), Heather McDonald (@HeatherMcDonald) and Greg Fitzsimmons (@GregFitzShow). Lake Bell from "A Good Old Fashion Orgy" is here.

5x131 - Usher

September 5, 2011

Round table comics Jo Koy (@JoKoy), Arden Myrin (@ardenmyrin) and Gary Valentine (@Gary_Valentine). It's Labor Day America and we're celebrating with Usher and Belvedere tonight.

5x132 - Gloria Estefan

September 6, 2011

Round table comics include Chris Franjola (@ChrisFranjola), Iliza Shlesinger (@iliza) and Matt Braunger (@Braunger). Gloria Estefan (@GloriaEstefan) is here with the latest on her new album, "Miss Little Havana."

5x133 - Dave Grohl

September 7, 2011

Dave Grohl is on the show tonight telling us all about the Foo Fighters album and tour. Comedian Bobby Lee, comedian Jen Kirkman and comedian Josh Wolf.

5x134 - James Marsden

September 8, 2011

James Marsden from the movie Straw Dogs is on the show tonight. Comedian Chris Hardwick, comedian Sarah Colonna and comedian Ben Gleib.

5x135 - Cooking with Roy

September 12, 2011

Round table comics include Brad Wollack (@BradWollack), Loni Love (@LoniLove) and TJ Miller (@nottjmiller). Tonight's show...Chelsea's big headed brother, gay book agent & Chuy are cooking food for Rosh Hashanah.

5x136 - Nick Swardson

September 13, 2011

Round table comics include Jo Koy (@JoKoy), Heather McDonald (@HeatherMcDonald) and Joe Matarese (@TheJoeMatarese). From the new movie "Bucky Larson: Born to Be a Star", Nick Swardson (@iAmNickSwardson) is here tonight.

5x137 - Kate Bosworth

September 14, 2011

Round table comics include Mo Mandel (@momandel), Natasha Leggero (@natashaleggero) and Gary Valentine (@Gary_Valentine). Kate Bosworth from the movie "Straw Dogs" is on the show tonight.

5x138 - Kathryn Hahn

September 15, 2011

Round table comics include Greg Proops (@GregProops), Fortune Feimster (@fortunefunny) and Josh Wolf (@JoshWolfComedy). From the new show "Free Agents" Kathryn Hahn is here.

5x139 - Anna Kendrick

September 19, 2011

Round table comics include Michael Yo (@MichaelYo), Chris Franjola (@ChrisFranjola), Jo Koy (@Jokoy). From the new movie "50/50," Anna Kendrick (@AnnaKendrick47) is on the show tonight.

5x140 - Anthony Mackie

September 20, 2011

Round table comics include Moshe Kasher (@moshekasher), Sarah Colonna (@SarahColonna) and Ross Mathews(@HelloRoss). Anthony Mackie (@TheRealAmackie) is here telling us about his latest movie, "Real Steel."

5x141 - Gavin Rossdale

September 21, 2011

Round table comics include Chris Hardwick (@nerdist), Jen Kirkman (@JenKirkman) and Lavell Crawford (@Lavellthacomic). Bush's Gavin Rossdale is on the show tonight with the latest on their new album, "Sea of Memories."

5x142 - Rachel Bilson

September 22, 2011

Round table comics include Bobby Lee (@bobbyleelive), Arden Myrin (@ardenmyrin) and Dov Davidoff (@dovdavidoff). Rachel Bilson is here telling us about her new show, "Hart of Dixie."