6x121 - Taye Diggs & Sarah Jane Morris

September 5, 2008

6x122 - Kobe Bryant, Tokio Hotel

September 9, 2008

6x123 - Martin Short

September 10, 2008

6x124 - Debra Messing, Buckcherry

September 11, 2008

6x125 - Darren Taylor, Terrence Howard, Michelle Monaghan

September 12, 2008

6x126 - Brad Garrett, Kerry Washington, Adam Perry Lang, Buckcherry

September 16, 2008

6x127 - Alyssa Milano, Stephen Merchant, Ne-Yo

September 17, 2008

6x128 - Ricky Gervais, Carla Gugino, Good Charlotte

September 18, 2008

6x129 - Michelle Monaghan, Cold War Kids

September 19, 2008

6x130 - Shia LaBeouf, January Jones, Nelly

September 22, 2008

6x131 - Dane Cook, Dylan & Cole Sprouse, Atmosphere

September 23, 2008

Comedian/actor Dane Cook (My Best Friend's Girl), actors Dylan & Col Sprouse (The Suite Life on Deck), musical guest Atmosphere

6x132 - Sandra Oh, the first "Dancing with the Stars" castoff, Foals

September 24, 2008

6x133 - Rob Lowe, Kimbo Slice, Chris Bianco

September 25, 2008

6x134 - Ricky Gervais, Carla Gugino, Good Charlotte

September 29, 2008

6x135 - Jon Favreau, Elvis Costello, the latest castoff from "Dancing with the Stars"

September 30, 2008

6x136 - Rosario Dawson, Jamie Kennedy, Gavin Rossdale

October 1, 2008

6x137 - Bill Maher, Jennifer Hudson

October 2, 2008

6x138 - Lucy Liu, John Slattery, Morgan Murphy

October 3, 2008

6x139 - Chris O'Donnell, the latest "Dancing with the Stars" castoff, Scars on Broadway

October 14, 2008

6x140 - David Alan Grier, Amaury Nolasco, Jessie Baylin

October 15, 2008

6x141 - Mark Wahlberg, Dania Ramirez

October 16, 2008

6x142 - Mila Kunis, Ben Stein, The Knux

October 17, 2008

6x143 - The latest "Dancing with the Stars" castoff, Jesse McCartney

October 21, 2008

6x144 - Amy Sedaris, Jonny Lee Miller, animal specialist Kirstin McMillan

October 22, 2008

6x145 - Colin Farrell, Natalie Zea, Lady GaGa

October 23, 2008

6x146 - Tom Arnold, Shea Whigham, Smashing Pumpkins

October 24, 2008

6x147 - Kristin Chenoweth, "Dancing with the Stars" castoff Cloris Leachman, Alkaline Trio

October 28, 2008

6x148 - Seth Rogen, Corbin Bleu, the Whigs

October 29, 2008

6x149 - Sarah Silverman, T.I.

October 30, 2008

6x150 - Nicolette Sheridan, Craig Robinson, N.E.R.D.

October 31, 2008

6x151 - Dr. Phil, Jordana Brewster, Eagles of Death Metal

November 3, 2008

6x152 - Sean Hayes, Susan Lucci, Kenny Maynes, John Legend

November 5, 2008

6x153 - Samuel L. Jackson, Bridget Regan, Hinder

November 6, 2008

6x154 - Terry Bradshaw, Jesse Metcalf

November 7, 2008

6x155 - Joshua Jackson, the latest

November 11, 2008

6x156 - Julia Louis Dreyfus, Dave Annable, Julianne Hough

November 12, 2008

6x157 - Daniel Craig, Olga Kurylenko

November 13, 2008

6x158 - Artie Lang, Candace Bushnell, T-Pain

November 14, 2008

6x159 - Kate Walsh, Mystery, the latest "Dancing with the Stars" castoff, Paramore

November 18, 2008

6x160 - Ellen Pompeo, Shaun White, Leona Lewis

November 19, 2008

6x161 - Jay Leno, the Hives

November 20, 2008

6x162 - Tracey Ullman, Baz Luhrmann

November 21, 2008

6x163 - Earvin "Magic" Johnson, Anna Torv, the Killers

November 24, 2008

6x164 - The winner of "Dancing with the Stars", the Jonas Brothers

November 25, 2008

6x165 - Reese Witherspoon, Craig and Paul Pumphrey, Scott Weiland

November 26, 2008

6x166 - Molly Shannon, Danny Masterson, Common

December 9, 2008

6x167 - Zooey Deschanel, Brian Austin Green, Adele

December 10, 2008

6x168 - Gabriel Macht, Sean "Diddy" Combs, Snow Patrol

December 11, 2008

6x169 - Amanda Peet, jet pack pilot Eric Scott, Freddy Rodriguez, Barry Manilow

December 12, 2008

6x170 - Courtney Cox, Bradley Cooper, the Cure

December 16, 2008

6x172 - Russell Brand, Thomas Kretschmann, All American Rejects

December 18, 2008

6x173 - Adam Sandler, Jaime King, Fall Out Boy

December 19, 2008