6x1 - Rena & Lee's Story

January 10, 2018

After meeting and falling in love at a bariatric rehab center, Lee and Rena are battling health and anger issues while making a desperate, second attempt to save their lives.

6x2 - Janine's Story

May 2, 2018

A woman whose extreme obesity has left her nearly immobile must overcome both her physical and emotional pain if she is ever to live a normal life again.

6x3 - Alicia's Story

May 9, 2018

A devoted girlfriend and loving aunt, Alicia is all smiles and laughter on the outside, but on the inside she is terrified that her addiction to food will kill her before she can marry her long-time love or watch her nieces grow up.

6x4 - Liz's Story

May 16, 2018

6x5 - Karina's Story

May 23, 2018

A woman with two children weighs more than 600 pounds, so she agrees to go on an extreme new diet, but her weight-loss efforts are threatened by her debilitating habits and a child’s health emergency.

6x6 - James B.'s Story

May 30, 2018

James LB Bonner spent his early life trying to prove himself to his adoptive family, but after losing a leg and battling obesity, LB must take a new path to save his health and his family relationships.

6x7 - Lisa's Story

June 6, 2018

Lisa's struggle with her weight begins as a child and significantly worsens after witnessing her brother's murder; now bedridden and unable to care for herself, she must lose the weight or she will never see her grandchildren grow up.

6x8 - Roberts Story

June 13, 2018

Now bedridden and unable to care for herself, Lisa must find a way to lose the weight or she will never see her grandchildren grow up.

6x9 - Tamy Lyn's Story

June 20, 2018

After years of a tumultuous relationship with her husband, Tamy's eating addiction causes her weight to balloon over 500 pounds; she becomes a hermit after years of shame and hopes to restart her life so she can better care for her son, Zachary.

6x10 - Benji & David's Story

June 27, 2018

Fearing that he'll suffer the same fate as older brother David, now 700 pounds and unable to work, Benji hopes to be able to support both himself and his brother on their life-or-death weight loss journey.

6x11 - Renee's Story

July 4, 2018

A former plus-size model and "big is beautiful" advocate, Renee realizes the mortal mistakes she made as her weight swells to 600 pounds and her health crumbles.

6x12 - Sarah's Story

July 11, 2018

A 24-year-old woman weighs more than 600 pounds and is fighting for her life after a difficult childhood with an abusive stepfather and drug-addicted mother.

6x13 - Schenee's Story

July 18, 2018

Devastated by two miscarriages due to her weight, Schenee is desperate to start a family and stop relying on her husband, Freddie, to take care of her; she hopes weight loss surgery will be able to fix her fertility issues as well as her marriage.

6x14 - Jennifer & Marissa's Story

July 25, 2018

Jennifer and her daughter, Marissa, are stuck in a co-dependent relationship that puts both of their lives in jeopardy, with a combined weight of more than 900 pounds; Jennifer strives to regain control before it's too late.

6x15 - Bettie Jo & Susan

April 18, 2018

A 400-lb. woman learns that she's pregnant, but wonders if she'll be able to deliver the baby without complications; a woman who lost 400 pounds is in a relationship, but it could be in jeopardy when her weight-loss journey stalls.

6x16 - Melissa Morris

April 25, 2018

Melissa has lost 500 pounds and saw her weight drop to 137 pounds, but now faces marital problems and life as a single mom, all while struggling with a gain of 150 pounds.

6x17 - One Ton Family Part 1

May 2, 2018

6x18 - One Ton Family Part 2

May 9, 2018

6x19 - Where Are They Now? - Kandi & Brandi

May 23, 2018

6x20 - Where Are They Now? - Erica

May 30, 2018

6x21 - Where Are They Now? - Diana & Ashley R

June 6, 2018

6x22 - Where Are They Now? - James & Cynthia

June 20, 2018

Back on Dr. Nowzaradan's program, James is suspected of cheating as he continues to gain weight and suffers a series of life-threatening illnesses. Cynthia continues to lose weight but seems satisfied to do so at her own pace.

6x23 - James & Cynthia

June 20, 2018

Back on Dr. Nowzaradan's program, James is suspected of cheating as he continues to gain weight and suffers a series of life-threatening illnesses; Cynthia continues to lose weight but seems satisfied to do so at her own pace.

6x24 - Doug

June 27, 2018

Losing over 200 pounds, Doug is now an active part of his family's lives and inspires a healthier lifestyle for them all. However, Doug's eating disorder and trouble finding his own identity threaten to derail his progress.

6x25 - Nicole & Ashley D.

July 11, 2018

Ashley hits an emotional wall and is desperate for skin surgery, but she is not losing any weight. After being evicted, Nicole is forced to move back to Ohio, which could impact her weight loss journey.