16x1 - Paul Giamatti

January 3, 2011

The media calls Barack Obama the "comeback kid," and Paul Giamatti says "rapscallion.

16x3 - Jimmy Wales

January 5, 2011

John McCain gets cranky, and Jimmy Wales imagines Wikipedia's relevance in 500 years.

16x4 - Patton Oswalt

January 6, 2011

Facebook refuses to disclose its financial results, and Patton Oswalt uses a prisoner ghostwriter.

16x5 - Denis Leary

January 10, 2011

John Oliver reports on the Arizona shootings in his PJs, and Denis Leary discusses "Suck on This Year.

16x6 - Colin Firth

January 11, 2011

John Oliver celebrates Verizon's iPhone announcement, and Colin Firth talks about "The King's Speech.

16x7 - Tim Pawlenty

January 12, 2011

Members of Congress introduce gun legislation, and Tim Pawlenty defends Republican rhetoric.

16x8 - Ron Howard

January 13, 2011

John Hodgman makes NASCAR more exciting, and Ron Howard shares his enthusiasm for show business.

16x9 - Peter Bergen

January 17, 2011

Michael Steele steps down as RNC chairman, and Peter Bergen talks about progress in Afghanistan.

16x10 - Neil deGrasse Tyson

January 18, 2011

Jon promises Sarah Palin a classy conversation and reveals his love for Neil deGrasse Tyson.

16x11 - Paul Clemens

January 19, 2011

Glenn Beck appears on the "Today" show, and Paul Clemens discusses blue-collar decline.

16x12 - Kambiz Hosseini & Saman Arbabi

January 20, 2011

Steve Cohen compares Republicans to Nazis, and Kambiz Hosseini and Saman Arbabi call Jon a prophet.

16x13 - Anand Giridharadas

January 24, 2011

Wyatt Cenac dons a parrot suit in Mississippi, and Anand Giridharadas tells Jon the truth.

16x14 - James Franco

January 25, 2011

A reporter searches for homeless talent, and Jon composes an ode to James Franco's Oscar nomination.

16x15 - Jonathan Alter

January 26, 2011

Michele Bachmann looks off camera, and Jonathan Alter examines Obama's plans for the future.

16x16 - T. Boone Pickens

January 27, 2011

Bill O'Reilly defends his Nazi analogies, and T. Boone Pickens wants America on an energy plan.

16x17 - Bill Gates

January 31, 2011

Egyptian forces use American tear gas canisters, and Bill Gates works on curing polio.

16x18 - Michael Steele

February 1, 2011

Conservatives turn into political hypochondriacs, and Michael Steele must prove his identity.

16x19 - Matthew Perry

February 2, 2011

Republicans close the rape loophole, and Matthew Perry talks about his happy friend.

16x20 - Adm. Michael Mullen

February 3, 2011

Justin Bieber switches bodies with Jon, and Mike Mullen talks about the crisis in Egypt.

16x21 - Edward Glaeser

February 14, 2011

16x22 - January Jones

February 15, 2011

16x23 - Brian Williams

February 16, 2011

Anchor and Managing Editor, NBC Nightly News. The award-winning journalist and friend-of-the-show stops by.

16x24 - Ed Gillespie

February 17, 2011

16x25 - Lisa Ling

February 21, 2011

16x26 - Anderson Cooper

February 22, 2011

16x27 - Donald Rumsfeld

February 23, 2011

16x28 - Austan Goolsbee

February 24, 2011

16x29 - Howard Stern

February 28, 2011

CNN anchors take viewer requests, and Howard Stern hopes to talk to Charlie Sheen.

16x30 - Prince Zeid Ra'ad

March 1, 2011

Prince Zeid Ra'ad Representative, The Hashemite Kingdom of Jordan The U.N. representative of Jordan discusses King Abdullah II's new book, "Our Last Best Chance.

16x31 - Allison Stanger

March 2, 2011

16x32 - Diane Ravitch

March 3, 2011

16x33 - Sen. Rand Paul

March 7, 2011

16x34 - Brian Christian

March 8, 2011

Author Brian Christian ('The Most Human Human: What Talking with Computers Teaches Us About What It Means to Be Alive').

16x35 - Aaron Eckhart

March 9, 2011

From 'Battle: Los Angeles,' actor Aaron Eckhart.

16x36 - Trey Parker & Matt Stone

March 10, 2011

'South Park,' creators Trey Parker and Matt Stone.

16x37 - Sarah Vowell

March 21, 2011

Author, "Unfamiliar Fishes." The author discusses her new book about American colonization of Hawaii in the 1800s.

16x38 - T.J. English

March 22, 2011

The author of "The Savage City" discusses his new book about murder and corruption in New York City during the 1960s and 70s.

16x39 - Richard Lewis

March 23, 2011

16x40 - Bret Baier

March 24, 2011

16x41 - Dr. Mansour O.El-Kikhia

March 28, 2011

Republicans want to lower the corporate tax rate, and Mansour O. El-Kikhia discusses Libya.

16x42 - Miguel Nicoleles

March 29, 2011

Joe Biden works the room at a war speech, and Miguel Nicolelis helps paralyzed people walk again.

16x43 - Jake Gyllenhaal

March 30, 2011

Republicans appeal to their narrow base, and Jake Gyllenhaal considers marrying a stranger.

16x44 - Norm MacDonald

March 31, 2011

CIA operatives might arm Libyan rebels, and Norm Macdonald wants to blow up his stupid high school.

16x45 - Billy Crystal

April 4, 2011

The comedian and actor discusses his role as a vampire in an upcoming Funny Or Die short.

16x46 - Colin Quinn

April 5, 2011

The comedian discusses his one-man Broadway show and special on HBO.

16x47 - Mike Huckabee

April 6, 2011

The former governor of Arkansas discusses his views on government, families and his latest book.

16x48 - Jamie Oliver

April 7, 2011

The chef talks about healthy cooking habits and the upcoming season of his Emmy-winning series.

16x49 - Foo Fighters

April 11, 2011

The rock band visits to perform a song from their latest album.

16x50 - Governor Deval Patrick

April 12, 2011

The governor of Massachusetts discusses his rise from poverty and what gives him hope for America's future.

16x51 - Tracy Morgan

April 13, 2011

The actor and comedian discusses his role in the upcoming animated film.

16x52 - Ricky Gervais

April 14, 2011

The comedian talks about his new HBO special with Jerry Seinfeld, Chris Rock and Louis C.K.