2x1 - Jennifer Aniston, Wayne Brady, Dr. Phil

September 13, 2021

Drew kicks off season two at the Paramount Lot in Los Angeles, with "The Morning Show" star Jennifer Aniston. Plus, "Let's Make A Deal" host Wayne Brady stops by and put Drew and Jennifer's game skills to the test, as they play to raise funds for Wagmor Pets Dog Rescue. Then, in an all-new Drew-Gooder, Drew shines a spotlight on Dolores Sheen, a.k.a. Aunt Dolores, who has spent the last 50 years educating children from underserved communities in Los Angeles. Plus, Drew is celebrating hometown pride, all week long, with viewers sharing tours of what makes their hometown so special and unique, including today's hometown spirit tour of Boston.

2x2 - Molly Shannon, David Arquette, Michael Vartan

September 14, 2021

It's a Never Been Kissed (1999) cast reunion, with guests Molly Shannon, David Arquette and Michael Vartan reuniting with host Drew Barrymore, two decades after the beloved film premiered. Plus, join Drew and RuPaul as they embark on a new journey together and head back to school to get their high school diploma equivalent. Then, in an all-new Wildflower, Drew spotlights women who have paved their own way to success, including a NASA Aerospace Engineer working on the Perseverance Rover, which is currently searching for signs of life on Mars. Plus, Drew is celebrating hometown pride, all week long, with viewers sharing tours of what makes their town so special and unique, including today's hometown spirit tour of Denver.

2x3 - Cameron Diaz

September 15, 2021

Cameron Diaz is joining Drew for a BFF hour, where the entire studio audience is filled with best friends. Plus, Cameron and Drew partake in an all-new Battle of the Bites: California Taco edition. Plus, Drew is celebrating hometown pride, all week long, with viewers sharing tours of what makes their town so special and unique, including today's hometown spirit tour of Indianapolis.

2x4 - Billie Eilish

September 16, 2021

Grammy Award-winning artist Billie Eilish stops by to chat about her new concert film, "Happier Than Ever: A Love Letter to Los Angeles." Plus, Missy Elliott helps Drew surprise the CEO of a non-profit dance company, who is a body-positive, all-inclusive dance enthusiast. Then, nationally syndicated radio host Big Boy, from Big Boy's Neighborhood, joins Drew fresh off of getting his star on the Hollywood Walk of Fame. Plus, Drew is celebrating hometown pride, all week long, with viewers sharing tours of what makes their town so special and unique, including today's hometown spirit tour of Phoenix.

2x6 - Awkwafina, Fat Joe, Fran Drescher, Benito Skinner

September 20, 2021

Drew will kicks off week two of her premiere event back in her New York studio with "Awkwafina is Nora from Queens" star Awkwafina. Plus, a surprise appearance from Fran Drescher. Drew will celebrates her love of New York with a tour of the Bronx with special tour guide Fat Joe. Plus, Benny Drama will joins Drew and Ross Mathews at the Drew's News desk. Plus, Drew is was celebrating hometown pride all week long with viewers sharing tours of what makes their town so special and unique including today's hometown spirit tour of Seattle.

2x7 - Carmelo Anthony, Antoni Porowski, Ziwe Fumudoh

September 21, 2021

Drew will continues celebrating New York week with Brooklyn-born NBA star Carmelo Anthony who was discusses his new memoir, "Where Tomorrows Aren't Promised." Drew will celebrates her love of New York with a tour of Brooklyn with special tour guide "Queer Eye" star Antoni Porowski. Plus, "Ziwe" star Ziwe Fumudoh will joins Drew at the Drew's News desk. Plus, Drew is was celebrating hometown pride all week long with viewers sharing tours of what makes their town so special and unique including today's hometown spirit tour of Orlando.

2x8 - John Stamos

September 22, 2021

John Stamos on his new podcast, "The Grand Scheme: Snatching Sinatra." Then, meet the three women, who was after finding out they all had the same cheating boyfriend, dumped him, bought a school bus naming it after their initials and hit the road for a once-in-a-lifetime road trip across the US. Plus, Drew and Ross Mathews are now taking their desk on the road and serving you the news sunny-side-up from Philadelphia. Drew is was celebrating hometown pride all week long with viewers sharing tours of what makes their town so special and unique including today's hometown spirit tour of Denver.

2x9 - Martha Stewart

September 23, 2021

Martha Stewart will stop by to with her own mail truck to help Drew make some special deliveries around New York City in this extra-special edition of "Dear Drew." TikTok star and upcycling expert Sarah Terensinski will shares her favorites tips on how to give a second life to everyday items. Plus, Drew and Ross Mathews are now taking their desk on the road and serving you the news sunny-side up from Washington D.C. Then, Drew is was celebrating hometown pride all week long with viewers sharing tours of what makes their town so special and unique including today's hometown spirit tour of Portland.

2x10 - Ben Platt

September 24, 2021

"Dear Evan Hansen" star Ben Platt. Plus, a very special correspondent Josie Geller will attends the "Dear Evan Hansen" press junket interviewing Ben Platt, Julianne Moore, Amy Adams, Danny Pino and Amandla Stenberg. Then, "CBS Mornings" co-host Nate Burleson will joins Drew at the Drew's News desk. Plus, in an all-new segment "New To Drew," Drew will tries out new things including street golfing. Then, Drew is was celebrating hometown pride all week long with viewers sharing tours of what makes their town so special and unique including today's hometown spirit tour of Dallas.

2x11 - Zanna Roberts Rassi, Chris Appleton, Brandice Daniel, Young Emperors, Max Greenfield

September 27, 2021

It's Drew's Mega-Makeover Hour packed with an big surprises, insider secrets and 25 transformations on Drew-Gooders you have to be see to believe. Drew's Mega Makeover Crew is was comprised of celebrity hairstylist Chris Appleton, founder of Harlem's Fashion Row Brandice Daniel, Co-founder of Milk Makeup Zanna Roberts Rassi and Instagram sensation The Young Emperors. Plus, "The Neighborhood" star Max Greenfield will joins in on the fun.

2x12 - Vanessa Hudgens, Zachariah Porter, Mikel Welch

September 28, 2021

"My Little Pony: A New Generation" star Vanessa Hudgens will stops by to be chat. Plus, Vanessa will joins Drew and TikTok sensation Zachariah Porter in the kitchen to whipping up with some of mystery puffs with an air fryer. Then, Drew Crew member interior designer Mikel Welch is was sharing five ways to update your outdoor space for under . Plus, Drew kicks off a new segment "Drew's Reviews," where Drew will reviews things sent in by viewers including Samin Nosrat's cookbook "Salt Fat Acid Heat."

2x13 - Padma Lakshmi, Damona Hoffman, Leo Kelly

September 29, 2021

"Taste the Nation" host Padma Lakshmi will joins Drew and shares some about hidden gems she's found across the country. Plus, Shirley Temple King Leo Kelly will joins Drew and Padma to taste test the tomato sauce from Padma's new book, "Tomatoes for Neela." Then, dating coach Damona Hoffman is was stopping by to be share tips on navigating digital dating at any age. Plus, Drew and Ross Mathews are serving the news sunny-side up in an all-new Drew's News.

2x14 - Elmo/Emmy Eaton/Pilar Valdes

September 30, 2021

"Not Too Late Show with Elmo" host Elmo will joins Drew. Plus, aspiring young journalist and creator of "7 Questions with Emmy," Emmy Eaton will joins Drew to ask Elmo some questions. Then, Drew's Crew member chef Pilar Valdes will stops by be to whipping up an Autumn Delicata Squash. Plus, Drew and Ross Mathews are now serving the news sunny-side up in an all-new Drew's News.

2x15 - Phoebe Robinson #2

October 1, 2021

"Please Don't Sit on my Bed in Your Outside Clothes" author and comedian Phoebe Robinson will stops by and plays a hilarious game of MASH with Drew. Then, Drew will sits down with a mother and daughter duo after the daughter wrote into the show seeking advice on how to repair her relationship with her mother. Plus, meet the latest members to join Drew's Good Dad Program, The Magic Dads from Memphis who was created a non-profit serving the youth in their community one bookbag, barbecue, and barbershop visit at a time.

2x16 - Bobby Flay, The Old Gays, Aliza Kelly

October 4, 2021

Drew will kicks off thrifty week, dedicating a whole week to learning the secrets to saving money and sharing inexpensive cooking hacks and budget-friendly design ideas. World-renowned chef Bobby Flay, will joins Drew to whip up a Juicy Lucy Pimento Cheeseburger from his new cookbook, "Beat Bobby Flay." Then, four friends who have become a social media sensation, The Old Gays, was help Drew interpret some popular slang phrases. Plus, an all-new Drew's News will where Drew and Ross Mathews serve the news sunny-side up.

2x17 - 50 Cent, Elizabeth and Ethan Finkelstein

October 5, 2021

Grammy Award-winning artist and star of "Power" 50 Cent will stops by and will plays a rousing game of "Is Fifty Thrifty?" with Drew. Then, Drew's whipping up in the kitchen one of her favorite easy, delicious, and cost-efficient meals Tortellini in Broth. Plus, meet the hosts of "Cheap Old Houses" Elizabeth and Ethan Finkelstein, who was share what it's like to travel the country in search of historical homes on the market at affordable prices.

2x18 - Jason Biggs, Ego Nwodin, Mikel Welch, Isaiah Garza

October 6, 2021

"Cash at Your Door" host Jason Biggs will joins Drew. Plus, Drew Crew member and celebrity interior designer Mikel Welch is was going head-to-head with a viewer in our thrift store design challenge. Plus, "SNL" cast member Ego Nwodim is was joining Drew at the Drew's News desk. Plus, meet Drew-Gooder Isaiah Garza who has been delivering random acts of kindness across the LA area.

2x19 - Dakota Johnson, Danny Seo, The Good in Five

October 7, 2021

Drew is taking Drew's News desk to the streets of New York, filming at the High Line with her special co-pilot, Dakota Johnson, actress and founder of curatorial platform, "Tea Time". Then, sustainability guru Danny Seo is sharing his favorite thrifty tips. Plus, in an all-new segment, "The Good in Five", Drew shares tips for improving your health in just five minutes, including your posture.

2x20 - The Estefans, Lisa Ling

October 8, 2021

Gloria Estefan, Lili Estefan and Emily Estefan will stop by to be chat about their new season of "Red Table Talk: The Estefans." Then, it's Beauty In A Box: Drugstore Edition, Drew is was helping one viewer with her beauty routine by sharing her favorite drug store finds. Plus, "This Is Life with Lisa Ling" host Lisa Ling is was joining Drew at the Drew's News desk.

2x21 - Adam Lambert, Tracey Cunningham, Ruby Ortiz

October 11, 2021

"Clash of the Cover Bands" Judge Adam Lambert will stops by to be chat and plays a rousing rapid-fire question game Makeup in a Minute. Then, it's hair color 101 with celebrity hairstylist Tracey Cunningham, who is sharing her trade tips and secrets to getting a hair color you love. Plus, one of the deserving viewer gets a hair refresh. All hour-long Drew is joined by an 11th-grade Spanish teacher from Brooklyn, Ruby Ortiz, who wrote in with a special request to be a guest co-host.

2x22 - Ike Barinholtz, Jonathan Toews, Seth Jones, Larray, Gillian Laub

October 12, 2021

"Chicago Party Aunt" star Ike Barinholtz will stops by to be chat and faces off against Chicago Blackhawks Players Jonathan Toews and Seth Jones in a rousing game of Chicago Champ. Plus, Drew kicks off Cookbook Countdown, in advance of the release of her first cookbook "Rebel Homemaker," and is joined by TikTok sensation Larray to be taste some loaded mac and cheeses. Then, photographer Gillian Laub, who has photographed some of the most influential people in the world, shares why she chose to turn the lens on herself and her family in her new book, "Family Matters."

2x23 - Chelsea Handler, Gillian Laub, Eitan Bernath

October 13, 2021

Comedian Chelsea Handler will stops by to be chat and will discuss her "Vaccinated and Horny Tour." Plus, TikTok sensation and Drew crew member Eitan Bernath will stops by to be share the latest food trends. Then, photographer Gillian Laub, who has an photographed some of the most influential people in the world, will shares why she chose to turn the lens on herself and her family in her new book, 'Family Matters."

2x24 - Episode 24

October 14, 2021

2x54 - Kathryn Hahn, Jane Levy, Lynn "Lynja" Davis

November 29, 2021

"The Shrink Next Door" star Kathryn Hahn will stops by to be chat. Plus, "Zoey's Extraordinary Christmas!" star Jane Levy will joins Drew and Ross Mathews at the Drew's News desk. Plus, Drew is was kicking off cookie week with the grandma who has gone viral on TikTok, Lynn "Lynja" Davis, who is a whipping up her favorite walnut crescent cookies.

2x55 - Brooke Shields, Erin French, Chiké Okonkwo

November 30, 2021

"A Castle For Christmas" star Brooke Shields will joins Drew and Ross Mathews at the Drew's News desk. Cookie week has continues with Chef and owner of The Lost Kitchen, one of the most sought-after restaurants in America, Erin French will stopping by to whip up her Nanny's molasses cookies with candied ginger. Plus, "La Brea" star Chiké Okonkwo will stops by to be chat.