2x65 - Meg Ryan, Adam Scott, Brian Fallon

September 12, 2016

James welcomes actress Meg Ryan, actor Adam Scott, and a musical performance by Brian Fallon.

2x66 - Donald Glover, Jimmie Johnson, Grouplove

September 13, 2016

James welcomes actor Donald Glover, NASCAR driver Jimmie Johnson, and a musical performance by Grouplove.

2x67 - Andy Samberg, Neil deGrasse Tyson, Globe of Steel, Mike Yung

September 14, 2016

James welcomes actor Andy Samberg, astrophysicist Neil deGrasse Tyson, and a motorcycle stunt performance Globe of Steel.

2x68 - Jimmy Kimmel, Patrick Dempsey, Renee Zellweger, CL

September 15, 2016

James welcomes talk show host Jimmy Kimmel, actor Patrick Dempsey, actress Renee Zellweger, and a musical performance by CL.

2x69 - Damon Wayans Sr., Michael Weatherly, DeAndre Jordan, Rizzle Kicks

September 19, 2016

2x70 - Alan Cumming, Jesse Tyler Ferguson, Nick Jonas

September 20, 2016

James welcomes actor Alan Cumming, actor Jesse Tyler Ferguson, and a talk with and musical performance by Nick Jonas.

2x71 - Kurt Russell, Ellen Pompeo, Kristen Bell, Banks + Steelz

September 21, 2016

James welcomes actor Kurt Russell, actress Ellen Pompeo, actress Kristen Bell, and a musical performance by Banks + Steelz.

2x72 - Lucy Liu, Terry Crews, Jack Hanna

September 22, 2016

James welcomes actress Lucy Liu, actor Terry Crews, and animal expert Jack Hanna.

2x73 - Lea Michele, Norm Macdonald, Nothing But Thieves

September 26, 2016

James welcomes comedian Norm Macdonald, actress Lea Michele, and a musical performance by Nothing But Thieves.

2x74 - Usain Bolt, Allison Janney, Owen Wilson, Eliza Skinner

September 27, 2016

James welcomes Olympic gold medalist Usain Bolt, actress Allison Janney, and actor Owen Wilson.

2x75 - Anjelica Huston, Wilmer Valderrama, Shawn Mendes

September 28, 2016

James welcomes actress Anjelica Huston, actor Wilmer Valderrama, and a talk with and musical performance by Shawn Mendes.

2x76 - Max Greenfield, Tig Notaro, Regina Spektor

September 29, 2016

James welcomes actor Max Greenfield, comedian Tig Notaro, and a musical performance by Regina Spektor.

2x77 - Jamie Lee Curtis, Kumail Nanjiani, Skylar Grey

October 3, 2016

2x78 - Rob Lowe, J.K. Simmons, Eliza Skinner

October 4, 2016

James welcomes actor Rob Lowe, actor J.K. Simmons, and a comedy performance by Eliza Skinner.

2x79 - Julie Chen, Beth Behrs, Kristin Chenoweth

October 5, 2016

James welcomes television host Julie Chen, actress Beth Behrs, and a talk and musical performance by Kristin Chenoweth.

2x80 - Zach Galifianakis, Taylor Lautner, Stevie Nicks

October 6, 2016

James welcomes actor Zach Galifianakis, actor Taylor Lautner, and a talk and musical performance by Stevie Nicks.

2x81 - Dakota Fanning, John Stamos, Shaquille O'Neal

October 17, 2016

James welcomes actress Dakota Fanning, actor John Stamos, and NBA legend Shaquille O'Neal.

2x82 - Shia LaBeouf, Cobie Smulders, Rachel Bloom

October 18, 2016

James welcomes actor Shia LaBeouf, actress Cobie Smulders, and actress Rachel Bloom.

2x83 - Tom Cruise, Anna Faris, Weezer

October 19, 2016

James welcomes actor Tom Cruise, actress Anna Faris, and a musical performance by Weezer.

2x84 - Cher, Gal Gadot, Pet Shop Boys

October 20, 2016

James welcomes singer Cher, actress Gal Gadot, and a musical performance by Pet Shop Boys.

2x85 - Nick Offerman, Ron Howard, Aldis Hodge, Norah Jones

October 24, 2016

James welcomes actor Nick Offerman, director Ron Howard, actor Aldis Hodge, and a musical performance by Norah Jones.

2x86 - Matt LeBlanc, Jeffrey Dean Morgan, Lady Gaga

October 25, 2016

James welcomes actor Matt LeBlanc, actor Jeffrey Dean Morgan, and a Carpool Karaoke with Lady Gaga.

2x87 - Ewan McGregor, Isla Fisher, Niall Horan

October 26, 2016

James welcomes actor Ewan McGregor, actress Isla Fisher, and a talk and performance by Niall Horan.

2x88 - Andrew Garfield, January Jones, LL Cool J

October 27, 2016

James welcomes actor Andrew Garfield, actress January Jones, and actor LL Cool J.

2x89 - Harry Connick Jr., Alice Eve, Lior Suchard

October 31, 2016

James welcomes talk show host Harry Connick Jr., actress Alice Eve, and a performance by mentalist Lior Suchard.

2x90 - Mark Consuelos, Zooey Deschanel, Kenny Chesney

November 1, 2016

James welcomes actor Mark Consuelos, actress Zooey Deschanel, and a musical performance by Kenny Chesney.

2x91 - Joel McHale, Julianne Hough, Gallant

November 2, 2016

James welcomes actor Joel McHale, actress Julianne Hough, and a musical performance by Gallant.

2x92 - Aaron Paul, Piper Perabo, Jack Hanna

November 3, 2016

James welcomes actor Aaron Paul, actress Piper Perabo, and animal expert Jack Hanna and his animals.

2x93 - Benedict Cumberbatch, Dennis Quaid, Molly Shannon, Nathaniel Rateliff and the Night Sweats

November 7, 2016

James welcomes actor Benedict Cumberbatch, actor Dennis Quaid, actress Molly Shannon, and a musical performance by Nathaniel Rateliff and the Night Sweats.

2x94 - John Lithgow, Ryan Phillippe, Kyra Sedgwick

November 9, 2016

James welcomes actor John Lithgow, actor Ryan Phillippe, and actress Kyra Sedgwick.

2x95 - Chris Tucker, Hailee Steinfeld, Shura

November 10, 2016

James welcomes actor Chris Tucker, actress Hailee Steinfeld, and a musical performance by Shura.

2x96 - Gina Rodriguez, Idina Menzel

November 14, 2016

James welcomes actress Gina Rodriguez and a talk with and musical performance by Idina Menzel.

2x97 - Matthew Broderick, Mandy Moore, Local Natives

November 15, 2016

James welcomes actror Matthew Broderick, actress Mandy Moore, and a musical performance by Local Natives.

2x98 - Kendall Jenner, Michael Strahan, Hey Violet

November 16, 2016

James welcomes reality TV personality Kendall Jenner, TV host Michael Strahan, and a musical performance by Hey Violet.

2x99 - Eddie Redmayne, Jessica Chastain, Iliza Shlesinger

November 17, 2016

James welcomes actor Eddie Redmayne, actress Jessica Chastain, and a stand-up comedy performance by Iliza Shlesinger.

2x100 - Anna Kendrick, Billy Eichner, Kurt Braunohler

November 21, 2016

James welcomes actress Anna Kendrick, actor Billy Eichner, and a comedy performance by Kurt Braunohler.

2x101 - Aaron Eckhart, Trevor Noah, Green Day

November 22, 2016

James welcomes actor Aaron Eckhart, late night television host Trevor Noah, and a musical performance by Green Day.

2x102 - Dana Carvey, Miles Teller, Usain Bolt

November 23, 2016

James welcomes actor Dana Carvey, actor Miles Teller, and Drop the Mic with Usain Bolt.

2x103 - Jessica Alba, Kate Mara, Ken Jeong

November 30, 2016

James welcomes actress Jessica Alba, actress Kate Mara, and actor Ken Jeong.

2x104 - Queen Latifah, Morris Chestnut, Tracey Ullman, Machine Gun Kelly x Camila Cabello

December 1, 2016

James welcomes actress Queen Latifah, actor Morris Chestnut, actress Tracey Ullman, and a musical performance by Machine Gun Kelly x Camila Cabello.

2x105 - Gael García Bernal, Lauren Cohan, John Legend

December 5, 2016

James welcomes actor Gael García Bernal, actress Lauren Cohan, and a musical performance by John Legend.

2x106 - Billy Crystal, Taron Egerton, CRX

December 6, 2016

James welcomes actor Billy Crystal, actor Taron Egerton, and a musical performance by CRX.

2x107 - Lily Tomlin, Madonna, Alison Sudol, Reggie Watts

December 7, 2016

James welcomes actress Lily Tomlin, actress Alison Sudol, and a comedy and musical performance by Reggie Watts.

2x108 - Tracee Ellis Ross, Stephen Fry, Lukas Graham

December 8, 2016

James welcomes actor Stephen Fry, actress Tracee Ellis Ross and a musical performance by Lukas Graham.

2x109 - Chris Pratt, Olivia Munn, She & Him

December 12, 2016

James welcomes actor Chris Pratt, actress Olivia Munn, and a musical performance by She & Him.

2x110 - Bruno Mars, Jennifer Lawrence, T.J. Miller

December 13, 2016

James welcomes actress Jennifer Lawrence, actor T.J. Miller, and Carpool Karaoke with Bruno Mars.

2x111 - Natalie Portman, Annette Bening, Neil Diamond

December 14, 2016

James welcomes actress Natalie Portman, actress Annette Bening, and a musical performance by Neil Diamond.

2x112 - Katie Holmes, Seth MacFarlane

December 15, 2016

James welcomes actress Katie Holmes, and a talk and musical performance by Seth MacFarlane.

2x113 - Milo Ventimiglia, Janelle Monáe, James Arthur

January 3, 2017

James welcomes actor Milo Ventimiglia, actress Janelle Monáe, and a musical performance by James Arthur.

2x114 - Jim Parsons, America Ferrera, Glass Animals

January 4, 2017

James welcomes actor Jim Parsons, actress America Ferrera, and a musical performance by Glass Animals.

2x116 - Neil Patrick Harris, Sienna Miller, Tom Ford

January 9, 2017

James welcomes actor Neil Patrick Harris, actress Sienna Miller, and director Tom Ford.

2x117 - Mark Wahlberg, Jeremy Renner, Joel Edgerton, Gabriel Iglesias

January 10, 2017

James welcomes actors Mark Wahlberg, Joel Edgerton, Jeremy Renner, and comedian Gabriel Iglesias.

2x118 - Khloe Kardashian, Pharrell Williams, Cameron Dallas

January 11, 2017

James welcomes reality TV Star Khloe Kardashian, internet personality Cameron Dallas, and recording artist Pharrell Williams.

2x119 - Bryan Cranston, Giovanni Ribisi, Jessica Biel, Jamie T

January 12, 2017

James welcomes actors Bryan Cranston, Giovanni Ribisi, actress Jessica Biel, and a musical performance from Jamie T.

2x120 - Kate Hudson, Anders Holm, Aaron Taylor-Johnson, Jim James

January 17, 2017

James welcomes actress Kate Hudson, actor Anders Holm, actor Aaron Taylor-Johnson, and a musical performance by Jim James.

2x121 - Vin Diesel, Woody Harrelson, Owen Wilson, Deepika Padukone, Ok Go

January 18, 2017

James welcomes actor Vin Diesel, actor Woody Harrelson, actor Owen Wilson, actress Deepika Padukone, and a musical performance by Ok Go.

2x122 - Chris Hardwick, Nina Dobrev, Fitz and the Tantrums

January 19, 2017

James welcomes television host Chris Hardwick, actress Nina Dobrev, and a musical performance from Fitz and the Tantrums.

2x123 - Drew Carey, Keke Palmer, Local Natives

January 30, 2017

James welcomes television host Drew Carey, actress Keke Palmer, and a musical performance by Local Natives.

2x124 - Johnny Galecki, Sting

January 31, 2017

James welcomes actor Johnny Galecki and a talk as well as a musical performance by Sting.

2x125 - Aaron Paul, Jenny Slate, Jermaine Fowler

February 1, 2017

James welcomes actor Aaron Paul, actress Jenny Slate, and actor Jermaine Fowler.

2x126 - Mindy Kaling, Bill Paxton

February 2, 2017

James welcomes actress Mindy Kaling and actor Bill Paxton.

2x127 - Ice Cube, Ike Barinholtz, Steve Aoki, Louis Tomlinson

February 13, 2017

James welcomes actor Ice Cube, actor Ike Barinholtz, and a musical performance from Steve Aoki and Louis Tomlinson.

2x128 - Katherine Heigl, Lars Ulrich, Andrew Rannells, Lisa Hannigan

February 14, 2017

James welcomes actress Katherine Heigl, actor Andrew Rannells, musician Lars Ulrich and a musical perfomance by Lisa Hannigan.

2x129 - Laura Dern, Zach Galifianakis, Glen Hansard

February 15, 2017

James welcomes actress Laura Dern,, actor Zach Galifianakis, and a musical performance by Glen Hansard.

2x130 - Matt Damon, Will Arnett, Bibi Bourelly

February 16, 2017

James welcomes actor Matt Damon, actor Will Arnett, and a musical performance by Bibi Bourelly.

2x131 - Trevor Noah, Laverne Cox, Luke Wilson, Noah Cyrus

February 21, 2017

James welcomes host Trevor Noah, actress Laverne Cox, actor Luke Wilson and a musical performance by Noah Cyrus.

2x132 - Bob Odenkirk, David Oyelowo, Bebe Rexha

February 22, 2017

James welcomes actor Bob Odenkirk and actor David Oyelowo, plus a musical performance by Bebe Rexha.

2x133 - Jordan Peele, Nick Kroll, Ryan Adams

February 23, 2017

James welcomes actors Jordan Peele and Nick Kroll, plus a musical performance by Ryan Adams.

2x134 - Chris O'Donnell, Sara Bareilles, Linkin Park ft Kiiara

February 27, 2017

James welcomes television host Chris O'Donnell,, singer Sara Bareilles, and a musical performance by Linkin Park ft Kiiara.

2x135 - Michelle Monaghan, Bradley Whitford, London Grammar

February 28, 2017

James welcomes actress Michelle Monaghan, actor Bradley Whitford, and a musical performance by London Grammar.

2x136 - Hayden Panettiere, Shirley MacLaine, Myq Kaplan

March 1, 2017

James welcomes actress Hayden Panettiere, and actress Shirley MacLaine and a stand-up routine by Myq Kaplan.

2x137 - Idris Elba, Jessica Lange, Scott Foley, Earl St. Clair

March 2, 2017

James welcomes actress Jessica Lange, actor Scott Foley, producer Idris Elba, and a musical performance by Earl St. Clair.

2x138 - Patrick Stewart, Rupert Grint, Dan Stevens, New Kids on the Block

March 6, 2017

James welcomes actor Patrick Stewart, actor Rupert Grint, actor Dan Stevens, and a musical performance by New Kids on the Block.

2x139 - Alec Baldwin, Kerry Washington, Jose Gonzalez

March 7, 2017

James welcome actor Alec Baldwin and actress Kerry Washington, plus a musical performance by Jose Gonzalez.

2x140 - Samuel L. Jackson, January Jones, Sting

March 8, 2017

James welcomes actor Samuel L. Jackson, actress January Jones and a musical performance by Sting.

2x141 - John Goodman, Adam Pally, Jack Hanna, Spoon

March 9, 2017

James welcomes actor John Goodman, actor Adam Pally, and Jack Hanna with his animals and a musical performance by Spoon.

2x142 - Leighton Meester, Dominic Monaghan, Blake Griffin, Judah & the Lion

March 13, 2017

James welcomes actor Dominic Monaghan, actress Leighton Meester, basketball player Blake Griffin, and a musical performance by Judah and the Lion.

2x143 - Gillian Jacobs, Jerrod Carmichael, Lea Michele

March 14, 2017

James welcomes actress Gillian Jacobs, comedian Jerrod Carmichael, and a musical performance by Lea Michele.

2x144 - Reese Witherspoon, Tony Goldwyn, Andy Shauf

March 15, 2017

James welcomes actress Reese Witherspoon, actor Tony Goldwyn and a musical performance by Andy Shauf.

2x145 - Vanessa Hudgens, Thomas Sadoski, Lil Rel Howery

March 16, 2017

James welcomes actress Vanessa Hudgens, actor Thomas Sadoski, and comedy performance by Lil Rel Howery.

2x146 - Abigail Spencer, Ben Platt, Tim Minchin, Take That

March 20, 2017

James welcomes actress Abigail Spencer, actor Ben Platt, comedian Tim Minchin, and a musical performance by Take That.

2x147 - Allison Williams, Darren Criss, The Band Perry

March 21, 2017

James welcomes actress Allison Williams, actor Darren Criss, and a musical performance by The Band Perry.

2x148 - Josh Gad, Judy Greer, Maggie Rogers

March 22, 2017

James welcomes actor Josh Gad, actress Judy Greer, and a musical performance by Maggie Rogers.

2x149 - Terrence Howard, Jenna Elfman, Nicole Scherzinger

March 23, 2017

James welcomes actor Terrence Howard, actress Jenna Elfman, and a musical performance by Nicole Scherzinger.

2x150 - J.J. Reddick, Scott Bakula, Pete Holmes, MisterWives

March 27, 2017

James welcomes basketball player J.J. Reddick, actor Scott Bakula, comedian Pete Holmes, and a musical performance by MisterWives.

2x151 - Kristen Bell, Cheryl Hines, Little Mix

March 28, 2017

James welcomes actress Kristen Bell, actress Cheryl Hines, and a musical performance by Little Mix.

2x152 - Victoria Beckham, Jessica Chastain, Lisa Kudrow

March 29, 2017

James welcomes designer Victoria Beckham, actress Jessica Chastain, and actress Lisa Kudrow.

2x153 - Adam Scott, Michael Peña, Bea Miller

March 30, 2017

James welcomes actor Adam Scott, actor Michael Pena, and a musical performance by Bea Miller.

2x154 - Stephen Curry, Chris Paul, Steve Nash

April 3, 2017

James welcomes NBA All-Stars Stephen Curry, Chris Paul and Steve Nash.

2x155 - Claire Danes, Christine Baranski, Jack McBrayer, Zara Larsson

April 4, 2017

James welcomes actress Claire Danes, actress Christine Baranski, actor Jack McBrayer, and a musical performance by Zara Larsson.

2x156 - Demi Lovato, Rupert Friend, Charlie Hunnam

April 5, 2017

James welcomes singer Demi Lovato, actor Charlie Hunnam, and actor Rupert Friend.

2x157 - Kumail Nanjiani, Riz Ahmed, Sabrina Carpenter

April 17, 2017

James welcomes actor Kumail Nanjiani, actor Riz Ahmed, and a musical performance by Sabrina Carpenter.

2x158 - Shania Twain, Tyrese Gibson, Whitney Cummings

April 18, 2017

James welcomes singer Shania Twain, actor Tyrese Gibson and comedian Whitney Cummings.

2x159 - Adam Sandler, Kevin James, Bastille

April 19, 2017

James welcomes actors Adam Sandler, and Kevin James, and a musical performance by Bastille.

2x160 - Anne Hathaway, Armie Hammer, Rob Delaney, 6lack

April 20, 2017

James welcomes actress Anne Hathaway, actor Armie Hammer, actor Rob Delaney, and a musical performance by 6lack.

2x161 - Jason Schwartzman, Nicole Richie, Geoffrey Rush, Depeche Mode

April 24, 2017

James welcomes actor Jason Schwartzman, actress Nicole Richie, actor Geoffrey Rush, with a musical performance by Depeche Mode.

2x162 - Amanda Peet, Kal Penn, Max Minghella, Kaleo

April 25, 2017

James welcomes actress Amanda Peet, actor Max Minghella, actor Kal Penn with a musical performance by Kaleo.

2x163 - Ludacris, Elisabeth Moss, Eugenio Derbez, The Head and the Heart

April 26, 2017

James welcomes rapper Ludacris, actress Elisabeth Moss, actor Eugenio Derbez, with a musical performance by The Head and the Heart.

2x164 - Kurt Russell, Thomas Middleditch, Russell Howard

April 27, 2017

James welcomes actor Kurt Russell, actor Thomas Middleditch, and comedian Russell Howard.

2x165 - Joel McHale, Jake Johnson, Lisa Hannigan

May 1, 2017

James welcomes actor Joel McHale and actor Jake Johnson plus a performance by Lisa Hannigan.