10x2 - Kaley Cuoco, Mike Birbiglia, Ari Lennox

September 20, 2022

Jimmy plays Virtual Reality Pictionary with guests Kaley Cuoco and Mike Birbiglia before welcoming musical guest Ari Lennox.

10x3 - Eli Manning, Chef José Andrés, Ana Fabrega, Michael Rowland

September 21, 2022

Jimmy plays Tonight at the Rock - Powered by Samsung Galaxy with Fortnite World Cup Champion Bugha before speaking with guests chef José Andrés and Ana Fabrega and welcoming stand-up comic Michael Rowland.

10x4 - Tyler Perry, Stephen A. Smith, Blood Orange

September 22, 2022

Jimmy reads his favorite tweets with the hashtag #WorstFirstDate before speaking with guests Tyler Perry and Stephen A. Smith and welcoming musical guest Blood Orange.

10x5 - Jon Hamm, Jurnee Smollett, The Smashing Pumpkins

September 23, 2022

Jimmy plays Hey Robot with Jon Hamm, speaks with guest Jurnee Smollett and welcomes musical guest The Smashing Pumpkins.

10x6 - Nick Kroll, Jenna Bush Hager, Raymond Lee, Colum Tyrrell

September 26, 2022

Jimmy shares his favorite inspirational quotes to help everyone kick off their week with good vibes, then catches up with Nick Kroll, Jenna Bush Hager and Raymond Lee before welcoming stand-up comic Colum Tyrrell.

10x7 - Kelly Ripa, Kid Cudi, Kid Cudi ft. Ty Dolla

September 27, 2022

Jimmy gets help from the audience to decide what he should post on Twitter in WeTweet, then catches up with Kelly Ripa and Kid Cudi before welcoming musical guest Kid Cudi featuring Ty Dolla .

10x8 - Miles Teller, Idina Menzel, Babyface ft. Baby Tate

September 28, 2022

Jimmy runs through the results of some little-known polls in Tonight Show Polls, then catches up with Miles Teller and Idina Menzel before welcoming musical guest Babyface featuring Baby Tate.

10x9 - Robert De Niro, Chloe Fineman, Arctic Monkeys

September 29, 2022

Jimmy reads his favorite tweets with the hashtag #IUsedToThink, then catches up with Robert De Niro and Chloe Fineman before welcoming musical guest Arctic Monkeys.

10x10 - Zac Efron, Debbie Harry, Lea Michele

September 30, 2022

Jimmy pens his weekly thank you notes, catches up with guests Zac Efron, Debbie Harry and Lea Michele and welcomes Michele for a musical performance.

10x11 - Naomi Watts, Jacob Batalon, Justin Thomas, Sam Hunt

October 3, 2022

Jimmy addresses Elon Musk unveiling the prototype for a humanoid robot, then catches up with Naomi Watts, Jacob Batalon and Justin Thomas before welcoming musical guest Sam Hunt.

10x12 - Ralph Macchio, Jennifer Beals, Lea Thompson, Modern English

October 4, 2022

Jimmy addresses Trump announcing a million defamation lawsuit against CNN, then catches up with Ralph Macchio, Jennifer Beals and Lea Thompson before welcoming musical guest Modern English.

10x13 - Reese Witherspoon, Kevin Nealon, Sabrina Wu

October 5, 2022

Jimmy addresses Trump asking the Supreme Court to overturn a ruling that allows the Justice Department to review documents seized from Mar-a-Lago, then catches up with Reese Witherspoon and Kevin Nealon before welcoming stand-up comedian Sabrina Wu.

10x14 - Jack Harlow, Dwyane Wade, Quavo & Takeoff

October 6, 2022

Jimmy and his co-host Jack Harlow compete in a basketball shooting contest using random objects, including a vase filled with applesauce, then catch up with Dwyane Wade before welcoming musical guests Quavo & Takeoff.

10x15 - Mike Myers, Sutton Foster, Killer Mike

October 7, 2022

Jimmy addresses Biden saying the world is at risk of a nuclear "Armageddon" amid rising tensions with Russia, then catches up with Mike Myers, Sutton Foster and Killer Mike before enjoying a musical performance from Killer Mike.

10x16 - Rachel Maddow, Noah Centineo, Fabien Frankel, Remi Wolf

October 10, 2022

Jimmy invites people all over the world to show off their talents for a brand-newShow Me Something Good and speaks with guests Rachel Maddow, Noah Centineo and Fabien Frankel before welcoming musical guest Remi Wolf.

10x17 - Pierce Brosnan, Charlie Puth, Kate del Castillo

October 11, 2022

Jimmy gets help from the audience to decide what he should post on Twitter in WeTweet, then catches up with Pierce Brosnan, musical guest Charlie Puth and Kate del Castillo.

10x18 - Dwayne Johnson, Camila Cabello, Ian Lara

October 12, 2022

Jimmy reads his favorite tweets with the hashtag #TextFail in an all-new Hashtags and catches up with guests Dwayne Johnson and Camila Cabello before welcoming comedian Ian Lara.

10x19 - Trevor Noah, Antoni Porowski, Andrea Campos, Lil Baby

October 13, 2022

Jimmy writes his weekly Thank You Notes and speaks with guests Trevor Noah, Antoni Porowski and Andrea Campos before welcoming musical guest Lil Baby.

10x20 - Taylor Swift, Meghan Trainor

October 24, 2022

Jimmy takes a moment to highlight some Tonight Show sponsors, then catches up with Taylor Swift and Meghan Trainor before enjoying a musical performance from Trainor.

10x21 - Sigourney Weaver, Michaela Coel, Zedd & Maren Morris

October 25, 2022

Jimmy gets help from the audience to decide what he should post on Twitter in WeTweet, then catches up with Sigourney Weaver and Michaela Coel before enjoying a musical performance from Zedd and Maren Morris.

10x22 - Jim Parsons, Rose Byrne, Isabel Hagen

October 26, 2022

Jimmy reviews some interesting user data released by Spotify, then catches up with Jim Parsons and Rose Byrne before welcoming stand-up comedian Isabel Hagen.

10x23 - Millie Bobby Brown, Michael Imperioli, Tegan and Sara

October 27, 2022

Jimmy reads his favorite tweets with the hashtag #LastMinuteCostumes, then catches up with Millie Bobby Brown and Michael Imperioli before welcoming musical guest Tegan and Sara.

10x24 - Lin-Manuel Miranda; Bobby Cannavale; JVKE

October 28, 2022

10x25 - Daniel Radcliffe; Winston Duke; Caroline Rhea

October 31, 2022

10x26 - Lupita Nyong'o; "Weird Al" Yankovic; Cameron Crowe; A Performance from Almost Famous

November 1, 2022

10x27 - George Lopez; Cole Hauser; LaTanya Richardson Jackson; Joey Bada$ with Men I Trust

November 2, 2022

10x28 - Hasan Minhaj; Bashir Salahuddin and Diallo Riddle; Paramore

November 3, 2022

10x29 - Mariah Carey, Marcus Mumford ft. Monica Martin

November 4, 2022

10x30 - Ryan Reynolds; Jen Psaki; Smino

November 7, 2022

10x31 - Octavia Spencer; Matthias Schweighöfer; Kurt Braunohler

November 9, 2022

10x32 - Will Ferrell; Lindsay Lohan; The 1975

November 10, 2022

10x33 - Sylvester Stallone; Linda Cardellini; Louis Tomlinson

November 11, 2022

10x34 - Bruce Springsteen; Chloe Grace Moretz

November 14, 2022

10x35 - Seth Rogen; Jeremy Pope; Bruce Springsteen

November 15, 2022

10x36 - Anya Taylor-Joy; Glen Powell; Patti Smith; Bruce Springsteen

November 16, 2022

10x37 - Jessica Chastain; Martha Steweart; The Smile

November 17, 2022

10x38 - Samuel L. Jackson; Neal Brennan; Wizkid

November 18, 2022

10x39 - Tim Allen; Lacey Chabert; From "Bluey:, Dave McCormack & Melanie; Brent Faiyaz

November 21, 2022

10x40 - Michael Strahan; Chef Daniel Humm; Cole Swindell

November 22, 2022

10x41 - Jesse Eisenberg; Madelyn Cline; Jacques Pepin

November 23, 2022

10x42 - Jerry Seinfeld; Adam Devine; Bruce Springsteen

November 24, 2022

10x43 - Zoe Saldana; James Austin Johnson; A Performance from & Juliet

November 28, 2022

10x44 - Whoopi Goldberg; Sam Worthington; Gabe LaBelle; Manuel Turizo

November 29, 2022

10x45 - Dolly Parton; Claire Foy; DOMi & JD BECK; Mac DeMarco

November 30, 2022

10x46 - Adam Sandler; Greta Gerwig; Dane Cook; Babyface Ray; Keke Palmer

December 1, 2022

10x47 - Kevin Bacon; Theo James; Jay Jurden

December 2, 2022

10x48 - Selena Gomez; Sebastian Maniscalco; beabadoobee

December 5, 2022

10x49 - Emma Thompson; Guillermo del Toro; Ashley McBryde; John Osborne

December 6, 2022

10x50 - Michelle Pfeiffer; Lil Rel Howery; Clive Davis; Goose

December 7, 2022

10x51 - Steve Martin; Martin Short; H.E.R.; Adam Blackstone; Mary Mary; Inayah; The BBE Big Band

December 8, 2022